A suspected case of olanzapine induced hyponatremia

Here we report a case of a 63-year-old male diagnosed with recurrent depressive disorder and current episode of severe depression with psychotic symptoms, developed hyponatremia soon after addition of olanzapine and increasing the dose of escitalopram. A possible causality association was establishe...

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Bibliographic Details
Published in:Indian journal of pharmacology 2014-07, Vol.46 (4), p.441-442
Main Authors: Bakhla, Ajay Kumar, Guria, Rishi Tuhin, Kumar, Abhishek
Format: Article
Language:English
Subjects:
Antipsychotic Agents - administration & dosage
Antipsychotic Agents - adverse effects
Antipsychotic Agents - therapeutic use
Benzodiazepines - administration & dosage
Benzodiazepines - adverse effects
Benzodiazepines - therapeutic use
Depressive Disorder - drug therapy
Diagnosis, Differential
Drug therapy
Drug Watch
Health aspects
Humans
Hyponatremia
Hyponatremia - chemically induced
Hyponatremia - diagnosis
Male
Mental depression
Middle Aged
Olanzapine
Pharmacology
Side effects
Sodium
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Summary:Here we report a case of a 63-year-old male diagnosed with recurrent depressive disorder and current episode of severe depression with psychotic symptoms, developed hyponatremia soon after addition of olanzapine and increasing the dose of escitalopram. A possible causality association was established with olanzapine, and the possible etiological reasons of this clinically significant risk were discussed.
ISSN:0253-7613
1998-3751
DOI:10.4103/0253-7613.135961