Relationship of muscle sympathetic nerve activity to insulin sensitivity

Purpose An association between insulin resistance and activation of the sympathetic nervous system has been reported in previous studies. However, potential interactions between insulin sensitivity and sympathetic neural mechanisms in healthy people remain poorly understood. We conducted a study to...

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Bibliographic Details
Published in:Clinical autonomic research 2014-04, Vol.24 (2), p.77-85
Main Authors: Curry, Timothy B., Hines, Casey N., Barnes, Jill N., Somaraju, Madhuri, Basu, Rita, Miles, John M., Joyner, Michael J., Charkoudian, Nisha
Format: Article
Language:English
Subjects:
Adolescent
Adult
Cardiology
Diabetes
Endocrinology
Female
Gastroenterology
Glucose Clamp Technique
Humans
Insulin Resistance - physiology
Male
Medicine
Medicine & Public Health
Middle Aged
Muscle, Skeletal - innervation
Neurology
Ophthalmology
Research Article
Sympathetic Nervous System - physiology
Young Adult
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Summary:Purpose An association between insulin resistance and activation of the sympathetic nervous system has been reported in previous studies. However, potential interactions between insulin sensitivity and sympathetic neural mechanisms in healthy people remain poorly understood. We conducted a study to determine the relationship between sympathetic activity and insulin resistance in young, healthy humans. Methods Thirty-seven healthy adults (18–35 years, BMI
ISSN:0959-9851
1619-1560
DOI:10.1007/s10286-014-0235-0