Effect of aging on microRNAs and regulation of pathogen recognition receptors

Highlights • Short non-coding microRNAs regulate gene expression and immune responses. • Dysregulation of pathogen recognition receptors and responses occurs in aging. • MiRNAs that modulate immune functions can change during aging. • Aging-associated miRNAs target pro-inflammatory networks such as...

Full description

Saved in:
Bibliographic Details
Published in:Current opinion in immunology 2014-08, Vol.29, p.29-37
Main Authors: Olivieri, Fabiola, Procopio, Antonio Domenico, Montgomery, Ruth R
Format: Article
Language:English
Subjects:
Adaptive Immunity
Aging
Allergy and Immunology
Animals
Humans
Immunity, Innate
Inflammation - immunology
MicroRNAs - genetics
MicroRNAs - immunology
Receptors, Immunologic - immunology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c572t-b8f422d099afa4eb97af077fffe703d3e244a2eb7f39161281f2ae47146a7c2f3
cites cdi_FETCH-LOGICAL-c572t-b8f422d099afa4eb97af077fffe703d3e244a2eb7f39161281f2ae47146a7c2f3
container_end_page 37
container_issue
container_start_page 29
container_title Current opinion in immunology
container_volume 29
creator Olivieri, Fabiola
Procopio, Antonio Domenico
Montgomery, Ruth R
description Highlights • Short non-coding microRNAs regulate gene expression and immune responses. • Dysregulation of pathogen recognition receptors and responses occurs in aging. • MiRNAs that modulate immune functions can change during aging. • Aging-associated miRNAs target pro-inflammatory networks such as NF-κB. • Aging-associated miRNAs could be therapeutic targets in immunosensecence.
doi_str_mv 10.1016/j.coi.2014.03.006
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4119513</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S0952791514000545</els_id><sourcerecordid>1562428273</sourcerecordid><originalsourceid>FETCH-LOGICAL-c572t-b8f422d099afa4eb97af077fffe703d3e244a2eb7f39161281f2ae47146a7c2f3</originalsourceid><addsrcrecordid>eNp9Uk1v1DAQtRCIbgs_gAvKkUuCvxKvhVSpqkpBKq3Ex3nkdcapl6y92Eml_nsctlTAgZOtmTdvRu89Ql4x2jDKurfbxkbfcMpkQ0VDafeErNha6ZoKxZ-SFdUtr5Vm7RE5znlLKW1bQZ-TIy5VpyUXK_Lpwjm0UxVdZQYfhiqGaudtip-vz3JlQl8lHObRTL40Cmhvpts4YChlG4fgf9XLH_dTTPkFeebMmPHlw3tCvr2_-Hr-ob66ufx4fnZV21bxqd6sneS8p1obZyRutDKOKuXKKYqKXiCX0nDcKCc06xhfM8cNSsVkZ5TlTpyQ0wPvft7ssLcYpmRG2Ce_M-keovHwdyf4WxjiHUjGdMtEIXjzQJDijxnzBDufLY6jCRjnDKztuORrrhYoO0CLKDkndI9rGIXFBthCsQEWG4AKKDaUmdd_3vc48Vv3Anh3AGBR6c5jgmw9Bou9L2JO0BfC_9Gf_jNtRx-8NeN3vMe8jXMKRX5gkDlQ-LLkYIkBk0sEZCt-AkC8roA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1562428273</pqid></control><display><type>article</type><title>Effect of aging on microRNAs and regulation of pathogen recognition receptors</title><source>Elsevier</source><creator>Olivieri, Fabiola ; Procopio, Antonio Domenico ; Montgomery, Ruth R</creator><creatorcontrib>Olivieri, Fabiola ; Procopio, Antonio Domenico ; Montgomery, Ruth R</creatorcontrib><description>Highlights • Short non-coding microRNAs regulate gene expression and immune responses. • Dysregulation of pathogen recognition receptors and responses occurs in aging. • MiRNAs that modulate immune functions can change during aging. • Aging-associated miRNAs target pro-inflammatory networks such as NF-κB. • Aging-associated miRNAs could be therapeutic targets in immunosensecence.</description><identifier>ISSN: 0952-7915</identifier><identifier>ISSN: 1879-0372</identifier><identifier>EISSN: 1879-0372</identifier><identifier>DOI: 10.1016/j.coi.2014.03.006</identifier><identifier>PMID: 24769423</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Adaptive Immunity ; Aging ; Allergy and Immunology ; Animals ; Humans ; Immunity, Innate ; Inflammation - immunology ; MicroRNAs - genetics ; MicroRNAs - immunology ; Receptors, Immunologic - immunology</subject><ispartof>Current opinion in immunology, 2014-08, Vol.29, p.29-37</ispartof><rights>Elsevier Ltd</rights><rights>2014 Elsevier Ltd</rights><rights>Copyright © 2014 Elsevier Ltd. All rights reserved.</rights><rights>2014 Elsevier Ltd. All rights reserved. 2014</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c572t-b8f422d099afa4eb97af077fffe703d3e244a2eb7f39161281f2ae47146a7c2f3</citedby><cites>FETCH-LOGICAL-c572t-b8f422d099afa4eb97af077fffe703d3e244a2eb7f39161281f2ae47146a7c2f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24769423$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Olivieri, Fabiola</creatorcontrib><creatorcontrib>Procopio, Antonio Domenico</creatorcontrib><creatorcontrib>Montgomery, Ruth R</creatorcontrib><title>Effect of aging on microRNAs and regulation of pathogen recognition receptors</title><title>Current opinion in immunology</title><addtitle>Curr Opin Immunol</addtitle><description>Highlights • Short non-coding microRNAs regulate gene expression and immune responses. • Dysregulation of pathogen recognition receptors and responses occurs in aging. • MiRNAs that modulate immune functions can change during aging. • Aging-associated miRNAs target pro-inflammatory networks such as NF-κB. • Aging-associated miRNAs could be therapeutic targets in immunosensecence.</description><subject>Adaptive Immunity</subject><subject>Aging</subject><subject>Allergy and Immunology</subject><subject>Animals</subject><subject>Humans</subject><subject>Immunity, Innate</subject><subject>Inflammation - immunology</subject><subject>MicroRNAs - genetics</subject><subject>MicroRNAs - immunology</subject><subject>Receptors, Immunologic - immunology</subject><issn>0952-7915</issn><issn>1879-0372</issn><issn>1879-0372</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNp9Uk1v1DAQtRCIbgs_gAvKkUuCvxKvhVSpqkpBKq3Ex3nkdcapl6y92Eml_nsctlTAgZOtmTdvRu89Ql4x2jDKurfbxkbfcMpkQ0VDafeErNha6ZoKxZ-SFdUtr5Vm7RE5znlLKW1bQZ-TIy5VpyUXK_Lpwjm0UxVdZQYfhiqGaudtip-vz3JlQl8lHObRTL40Cmhvpts4YChlG4fgf9XLH_dTTPkFeebMmPHlw3tCvr2_-Hr-ob66ufx4fnZV21bxqd6sneS8p1obZyRutDKOKuXKKYqKXiCX0nDcKCc06xhfM8cNSsVkZ5TlTpyQ0wPvft7ssLcYpmRG2Ce_M-keovHwdyf4WxjiHUjGdMtEIXjzQJDijxnzBDufLY6jCRjnDKztuORrrhYoO0CLKDkndI9rGIXFBthCsQEWG4AKKDaUmdd_3vc48Vv3Anh3AGBR6c5jgmw9Bou9L2JO0BfC_9Gf_jNtRx-8NeN3vMe8jXMKRX5gkDlQ-LLkYIkBk0sEZCt-AkC8roA</recordid><startdate>20140801</startdate><enddate>20140801</enddate><creator>Olivieri, Fabiola</creator><creator>Procopio, Antonio Domenico</creator><creator>Montgomery, Ruth R</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20140801</creationdate><title>Effect of aging on microRNAs and regulation of pathogen recognition receptors</title><author>Olivieri, Fabiola ; Procopio, Antonio Domenico ; Montgomery, Ruth R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c572t-b8f422d099afa4eb97af077fffe703d3e244a2eb7f39161281f2ae47146a7c2f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adaptive Immunity</topic><topic>Aging</topic><topic>Allergy and Immunology</topic><topic>Animals</topic><topic>Humans</topic><topic>Immunity, Innate</topic><topic>Inflammation - immunology</topic><topic>MicroRNAs - genetics</topic><topic>MicroRNAs - immunology</topic><topic>Receptors, Immunologic - immunology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Olivieri, Fabiola</creatorcontrib><creatorcontrib>Procopio, Antonio Domenico</creatorcontrib><creatorcontrib>Montgomery, Ruth R</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Current opinion in immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Olivieri, Fabiola</au><au>Procopio, Antonio Domenico</au><au>Montgomery, Ruth R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of aging on microRNAs and regulation of pathogen recognition receptors</atitle><jtitle>Current opinion in immunology</jtitle><addtitle>Curr Opin Immunol</addtitle><date>2014-08-01</date><risdate>2014</risdate><volume>29</volume><spage>29</spage><epage>37</epage><pages>29-37</pages><issn>0952-7915</issn><issn>1879-0372</issn><eissn>1879-0372</eissn><abstract>Highlights • Short non-coding microRNAs regulate gene expression and immune responses. • Dysregulation of pathogen recognition receptors and responses occurs in aging. • MiRNAs that modulate immune functions can change during aging. • Aging-associated miRNAs target pro-inflammatory networks such as NF-κB. • Aging-associated miRNAs could be therapeutic targets in immunosensecence.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>24769423</pmid><doi>10.1016/j.coi.2014.03.006</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0952-7915
ispartof Current opinion in immunology, 2014-08, Vol.29, p.29-37
issn 0952-7915
1879-0372
1879-0372
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4119513
source Elsevier
subjects Adaptive Immunity
Aging
Allergy and Immunology
Animals
Humans
Immunity, Innate
Inflammation - immunology
MicroRNAs - genetics
MicroRNAs - immunology
Receptors, Immunologic - immunology
title Effect of aging on microRNAs and regulation of pathogen recognition receptors
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-22T20%3A20%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effect%20of%20aging%20on%20microRNAs%20and%20regulation%20of%20pathogen%20recognition%20receptors&rft.jtitle=Current%20opinion%20in%20immunology&rft.au=Olivieri,%20Fabiola&rft.date=2014-08-01&rft.volume=29&rft.spage=29&rft.epage=37&rft.pages=29-37&rft.issn=0952-7915&rft.eissn=1879-0372&rft_id=info:doi/10.1016/j.coi.2014.03.006&rft_dat=%3Cproquest_pubme%3E1562428273%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c572t-b8f422d099afa4eb97af077fffe703d3e244a2eb7f39161281f2ae47146a7c2f3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1562428273&rft_id=info:pmid/24769423&rfr_iscdi=true