Effect of chlorhexidine chip in the treatment of chronic periodontitis

• Published in: Journal of natural science, biology and medicine biology and medicine, 2014-07, Vol.5 (2), p.268-272
• Main Authors: Kumar, A, Ramesh Reddy, B, Chava, Vijay
• Format: Article
• Language: English
• Subjects: Care and treatment; Chlorhexidine; Dosage and administration; Drug delivery systems; Drugs; Original; Periodontitis; Testing; Vehicles
• ISSN: 0976-9668; 2229-7707
• DOI: 10.4103/0976-9668.136159

Aims: The evaluation of clinical and specific microbiological changes associated with chlorhexidine chip in the chronic periodontitis patients. Materials and Methods: A total of 30 chronic periodontitis patients (aged 20-65 years) having pocket depth of ≥5 mm in molar teeth were selected and randomly divided into following treatment groups: Group 1 - Scaling and root planning (SRP), Group 2 - SRP along with chlorhexidine chip and Group 3 - Only chlorhexidine chip. The clinical and microbial parameters were recorded at baseline and 1 and 3 months post-treatment as above. Benzoyl-DL-arginine-naphthylamide (BANA) chair side test was used for estimation of specific microbiota. Results: Gingival index, probing pocket depth and clinical attachment level scores in selected teeth within the groups at different time intervals was significantly (P < 0.001) different. Although, the comparison between groups for specific microbiota in selected sites at different intervals was not statistically significant at baseline and 1 month, it reached statistical significance at 3 rd month post-treatment. Although significant reductions in percentage of BANA positive sites were observed in all three groups, the Group 2 had significantly greater percentage of BANA negative sites. Conclusion: Local drug delivery using chlorhexidine chip enhances the benefit of SRP in the treatment of chronic periodontitis.