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Differences in the reinstatement of ethanol seeking with ganaxolone and gaboxadol
Highlights • A GABAA receptor-active neurosteroid analog, ganaxolone, reinstated ethanol seeking in mice. • An extrasynaptic GABAA receptor agonist, gaboxadol (THIP), did not reinstate ethanol seeking. • Direct extrasynaptic GABAA receptor activation is not sufficient to reinstate ethanol seeking....
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Published in: | Neuroscience 2014-07, Vol.272, p.180-187 |
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Main Authors: | , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | Highlights • A GABAA receptor-active neurosteroid analog, ganaxolone, reinstated ethanol seeking in mice. • An extrasynaptic GABAA receptor agonist, gaboxadol (THIP), did not reinstate ethanol seeking. • Direct extrasynaptic GABAA receptor activation is not sufficient to reinstate ethanol seeking. |
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ISSN: | 0306-4522 1873-7544 |
DOI: | 10.1016/j.neuroscience.2014.04.065 |