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Type 2 diabetes, socioeconomic status and risk of cancer in Scotland 2001–2007
Aims/hypothesis The objective of this study was to use Scottish national data to assess the influence of type 2 diabetes on the risk of cancer at 16 different sites, while specifically investigating the role of confounding by socioeconomic status in the diabetes–cancer relationship. Methods All peop...
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| Published in: | Diabetologia 2013-08, Vol.56 (8), p.1712-1715 |
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| container_title | Diabetologia |
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| creator | Walker, J. J. Brewster, D. H. Colhoun, H. M. Fischbacher, C. M. Leese, G. P. Lindsay, R. S. McKnight, J. A. Philip, S. Sattar, N. Stockton, D. L. Wild, S. H. |
| description | Aims/hypothesis
The objective of this study was to use Scottish national data to assess the influence of type 2 diabetes on the risk of cancer at 16 different sites, while specifically investigating the role of confounding by socioeconomic status in the diabetes–cancer relationship.
Methods
All people in Scotland aged 55–79 years diagnosed with any of the cancers of interest during the period 2001–2007 were identified and classified by the presence/absence of co-morbid type 2 diabetes. The influence of diabetes on cancer risk for each site was assessed via Poisson regression, initially with adjustment for age only, then adjusted for both age and socioeconomic status.
Results
There were 4,285 incident cancers in people with type 2 diabetes. RR for any cancers (adjusted for age only) was 1.11 (95% CI 1.05, 1.17) for men and 1.33 (1.28, 1.40) for women. Corresponding values after additional adjustment for socioeconomic status were 1.10 (1.04, 1.15) and 1.31 (1.25, 1.38), respectively. RRs for individual cancer sites varied markedly.
Conclusions/interpretation
Socioeconomic status was found to have little influence on the association between type 2 diabetes and cancer. |
| doi_str_mv | 10.1007/s00125-013-2937-6 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4131139</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3010458011</sourcerecordid><originalsourceid>FETCH-LOGICAL-c500t-7121a68718bd81ee2dbf442872cc077fc42beb1b7f3109e4f90890f1fa0a0cd03</originalsourceid><addsrcrecordid>eNp1kc9qFTEUxkOx2NurD9CNBIrQRUfPSWaSmY0gRa1QsNAK7kImk9S0cyfXZEboznfwDX0SM9xr_4Grs_h-58v58hFygPAGAeTbBICsKgB5wRouC7FDFlhyVkDJ6mdkMcsF1uLbHtlP6RoAeFWK52SPcSEQQSzI-eXt2lJGO69bO9p0TFMwPlgThrDyhqZRj1Oieuho9OmGBkeNHoyN1A_0woSxnyWWX_rz63ce8gXZdbpP9uV2LsnXjx8uT06Lsy-fPp-8PytMBTAWEhlqUUus265Ga1nXujJfLZkxIKUzJWtti610HKGxpWugbsCh06DBdMCX5N3Gdz21K9sZO4xR92od_UrHWxW0V4-VwX9XV-GnKpEj8iYbHG0NYvgx2TSqlU_G9jmQDVNSM1MzVkOZ0cMn6HWY4pDjZUpy3ogcPFO4oUwMKUXr7o5BUHNfatOXyn2puS8l8s6rhynuNv4VlIHXW0Ano3sX8-f7dM_JimOVDZeEbbiUpeHKxgcn_vf1vz0jq_4</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1373396007</pqid></control><display><type>article</type><title>Type 2 diabetes, socioeconomic status and risk of cancer in Scotland 2001–2007</title><source>Springer Nature</source><creator>Walker, J. J. ; Brewster, D. H. ; Colhoun, H. M. ; Fischbacher, C. M. ; Leese, G. P. ; Lindsay, R. S. ; McKnight, J. A. ; Philip, S. ; Sattar, N. ; Stockton, D. L. ; Wild, S. H.</creator><creatorcontrib>Walker, J. J. ; Brewster, D. H. ; Colhoun, H. M. ; Fischbacher, C. M. ; Leese, G. P. ; Lindsay, R. S. ; McKnight, J. A. ; Philip, S. ; Sattar, N. ; Stockton, D. L. ; Wild, S. H. ; Scottish Diabetes Research Network (SDRN) Epidemiology Group ; on behalf of the Scottish Diabetes Research Network (SDRN) Epidemiology Group</creatorcontrib><description>Aims/hypothesis
The objective of this study was to use Scottish national data to assess the influence of type 2 diabetes on the risk of cancer at 16 different sites, while specifically investigating the role of confounding by socioeconomic status in the diabetes–cancer relationship.
Methods
All people in Scotland aged 55–79 years diagnosed with any of the cancers of interest during the period 2001–2007 were identified and classified by the presence/absence of co-morbid type 2 diabetes. The influence of diabetes on cancer risk for each site was assessed via Poisson regression, initially with adjustment for age only, then adjusted for both age and socioeconomic status.
Results
There were 4,285 incident cancers in people with type 2 diabetes. RR for any cancers (adjusted for age only) was 1.11 (95% CI 1.05, 1.17) for men and 1.33 (1.28, 1.40) for women. Corresponding values after additional adjustment for socioeconomic status were 1.10 (1.04, 1.15) and 1.31 (1.25, 1.38), respectively. RRs for individual cancer sites varied markedly.
Conclusions/interpretation
Socioeconomic status was found to have little influence on the association between type 2 diabetes and cancer.</description><identifier>ISSN: 0012-186X</identifier><identifier>EISSN: 1432-0428</identifier><identifier>DOI: 10.1007/s00125-013-2937-6</identifier><identifier>PMID: 23661106</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Age ; Aged ; Biological and medical sciences ; Cancer ; Diabetes ; Diabetes Mellitus, Type 2 - epidemiology ; Diabetes. Impaired glucose tolerance ; Endocrine pancreas. Apud cells (diseases) ; Endocrinopathies ; Epidemiology ; Etiopathogenesis. Screening. Investigations. Target tissue resistance ; Female ; Human Physiology ; Humans ; Information services ; Internal Medicine ; Investigations ; Male ; Medical sciences ; Medicine ; Medicine & Public Health ; Metabolic Diseases ; Middle Aged ; Multiple tumors. Solid tumors. Tumors in childhood (general aspects) ; Neoplasms - epidemiology ; Population ; Prostate ; Registration ; Scotland - epidemiology ; Short Communication ; Social Class ; Socioeconomic factors ; Tumors</subject><ispartof>Diabetologia, 2013-08, Vol.56 (8), p.1712-1715</ispartof><rights>Springer-Verlag Berlin Heidelberg 2013</rights><rights>2014 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c500t-7121a68718bd81ee2dbf442872cc077fc42beb1b7f3109e4f90890f1fa0a0cd03</citedby><cites>FETCH-LOGICAL-c500t-7121a68718bd81ee2dbf442872cc077fc42beb1b7f3109e4f90890f1fa0a0cd03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,777,781,882,27905,27906</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=27531501$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23661106$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Walker, J. J.</creatorcontrib><creatorcontrib>Brewster, D. H.</creatorcontrib><creatorcontrib>Colhoun, H. M.</creatorcontrib><creatorcontrib>Fischbacher, C. M.</creatorcontrib><creatorcontrib>Leese, G. P.</creatorcontrib><creatorcontrib>Lindsay, R. S.</creatorcontrib><creatorcontrib>McKnight, J. A.</creatorcontrib><creatorcontrib>Philip, S.</creatorcontrib><creatorcontrib>Sattar, N.</creatorcontrib><creatorcontrib>Stockton, D. L.</creatorcontrib><creatorcontrib>Wild, S. H.</creatorcontrib><creatorcontrib>Scottish Diabetes Research Network (SDRN) Epidemiology Group</creatorcontrib><creatorcontrib>on behalf of the Scottish Diabetes Research Network (SDRN) Epidemiology Group</creatorcontrib><title>Type 2 diabetes, socioeconomic status and risk of cancer in Scotland 2001–2007</title><title>Diabetologia</title><addtitle>Diabetologia</addtitle><addtitle>Diabetologia</addtitle><description>Aims/hypothesis
The objective of this study was to use Scottish national data to assess the influence of type 2 diabetes on the risk of cancer at 16 different sites, while specifically investigating the role of confounding by socioeconomic status in the diabetes–cancer relationship.
Methods
All people in Scotland aged 55–79 years diagnosed with any of the cancers of interest during the period 2001–2007 were identified and classified by the presence/absence of co-morbid type 2 diabetes. The influence of diabetes on cancer risk for each site was assessed via Poisson regression, initially with adjustment for age only, then adjusted for both age and socioeconomic status.
Results
There were 4,285 incident cancers in people with type 2 diabetes. RR for any cancers (adjusted for age only) was 1.11 (95% CI 1.05, 1.17) for men and 1.33 (1.28, 1.40) for women. Corresponding values after additional adjustment for socioeconomic status were 1.10 (1.04, 1.15) and 1.31 (1.25, 1.38), respectively. RRs for individual cancer sites varied markedly.
Conclusions/interpretation
Socioeconomic status was found to have little influence on the association between type 2 diabetes and cancer.</description><subject>Age</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Cancer</subject><subject>Diabetes</subject><subject>Diabetes Mellitus, Type 2 - epidemiology</subject><subject>Diabetes. Impaired glucose tolerance</subject><subject>Endocrine pancreas. Apud cells (diseases)</subject><subject>Endocrinopathies</subject><subject>Epidemiology</subject><subject>Etiopathogenesis. Screening. Investigations. Target tissue resistance</subject><subject>Female</subject><subject>Human Physiology</subject><subject>Humans</subject><subject>Information services</subject><subject>Internal Medicine</subject><subject>Investigations</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Metabolic Diseases</subject><subject>Middle Aged</subject><subject>Multiple tumors. Solid tumors. Tumors in childhood (general aspects)</subject><subject>Neoplasms - epidemiology</subject><subject>Population</subject><subject>Prostate</subject><subject>Registration</subject><subject>Scotland - epidemiology</subject><subject>Short Communication</subject><subject>Social Class</subject><subject>Socioeconomic factors</subject><subject>Tumors</subject><issn>0012-186X</issn><issn>1432-0428</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNp1kc9qFTEUxkOx2NurD9CNBIrQRUfPSWaSmY0gRa1QsNAK7kImk9S0cyfXZEboznfwDX0SM9xr_4Grs_h-58v58hFygPAGAeTbBICsKgB5wRouC7FDFlhyVkDJ6mdkMcsF1uLbHtlP6RoAeFWK52SPcSEQQSzI-eXt2lJGO69bO9p0TFMwPlgThrDyhqZRj1Oieuho9OmGBkeNHoyN1A_0woSxnyWWX_rz63ce8gXZdbpP9uV2LsnXjx8uT06Lsy-fPp-8PytMBTAWEhlqUUus265Ga1nXujJfLZkxIKUzJWtti610HKGxpWugbsCh06DBdMCX5N3Gdz21K9sZO4xR92od_UrHWxW0V4-VwX9XV-GnKpEj8iYbHG0NYvgx2TSqlU_G9jmQDVNSM1MzVkOZ0cMn6HWY4pDjZUpy3ogcPFO4oUwMKUXr7o5BUHNfatOXyn2puS8l8s6rhynuNv4VlIHXW0Ano3sX8-f7dM_JimOVDZeEbbiUpeHKxgcn_vf1vz0jq_4</recordid><startdate>20130801</startdate><enddate>20130801</enddate><creator>Walker, J. J.</creator><creator>Brewster, D. H.</creator><creator>Colhoun, H. M.</creator><creator>Fischbacher, C. M.</creator><creator>Leese, G. P.</creator><creator>Lindsay, R. S.</creator><creator>McKnight, J. A.</creator><creator>Philip, S.</creator><creator>Sattar, N.</creator><creator>Stockton, D. L.</creator><creator>Wild, S. H.</creator><general>Springer Berlin Heidelberg</general><general>Springer</general><general>Springer Nature B.V</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T5</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20130801</creationdate><title>Type 2 diabetes, socioeconomic status and risk of cancer in Scotland 2001–2007</title><author>Walker, J. J. ; Brewster, D. H. ; Colhoun, H. M. ; Fischbacher, C. M. ; Leese, G. P. ; Lindsay, R. S. ; McKnight, J. A. ; Philip, S. ; Sattar, N. ; Stockton, D. L. ; Wild, S. H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c500t-7121a68718bd81ee2dbf442872cc077fc42beb1b7f3109e4f90890f1fa0a0cd03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Age</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Cancer</topic><topic>Diabetes</topic><topic>Diabetes Mellitus, Type 2 - epidemiology</topic><topic>Diabetes. Impaired glucose tolerance</topic><topic>Endocrine pancreas. Apud cells (diseases)</topic><topic>Endocrinopathies</topic><topic>Epidemiology</topic><topic>Etiopathogenesis. Screening. Investigations. Target tissue resistance</topic><topic>Female</topic><topic>Human Physiology</topic><topic>Humans</topic><topic>Information services</topic><topic>Internal Medicine</topic><topic>Investigations</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Metabolic Diseases</topic><topic>Middle Aged</topic><topic>Multiple tumors. Solid tumors. Tumors in childhood (general aspects)</topic><topic>Neoplasms - epidemiology</topic><topic>Population</topic><topic>Prostate</topic><topic>Registration</topic><topic>Scotland - epidemiology</topic><topic>Short Communication</topic><topic>Social Class</topic><topic>Socioeconomic factors</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Walker, J. J.</creatorcontrib><creatorcontrib>Brewster, D. H.</creatorcontrib><creatorcontrib>Colhoun, H. M.</creatorcontrib><creatorcontrib>Fischbacher, C. 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H.</creatorcontrib><creatorcontrib>Scottish Diabetes Research Network (SDRN) Epidemiology Group</creatorcontrib><creatorcontrib>on behalf of the Scottish Diabetes Research Network (SDRN) Epidemiology Group</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Immunology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Diabetologia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Walker, J. J.</au><au>Brewster, D. H.</au><au>Colhoun, H. M.</au><au>Fischbacher, C. M.</au><au>Leese, G. P.</au><au>Lindsay, R. S.</au><au>McKnight, J. A.</au><au>Philip, S.</au><au>Sattar, N.</au><au>Stockton, D. L.</au><au>Wild, S. H.</au><aucorp>Scottish Diabetes Research Network (SDRN) Epidemiology Group</aucorp><aucorp>on behalf of the Scottish Diabetes Research Network (SDRN) Epidemiology Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Type 2 diabetes, socioeconomic status and risk of cancer in Scotland 2001–2007</atitle><jtitle>Diabetologia</jtitle><stitle>Diabetologia</stitle><addtitle>Diabetologia</addtitle><date>2013-08-01</date><risdate>2013</risdate><volume>56</volume><issue>8</issue><spage>1712</spage><epage>1715</epage><pages>1712-1715</pages><issn>0012-186X</issn><eissn>1432-0428</eissn><abstract>Aims/hypothesis
The objective of this study was to use Scottish national data to assess the influence of type 2 diabetes on the risk of cancer at 16 different sites, while specifically investigating the role of confounding by socioeconomic status in the diabetes–cancer relationship.
Methods
All people in Scotland aged 55–79 years diagnosed with any of the cancers of interest during the period 2001–2007 were identified and classified by the presence/absence of co-morbid type 2 diabetes. The influence of diabetes on cancer risk for each site was assessed via Poisson regression, initially with adjustment for age only, then adjusted for both age and socioeconomic status.
Results
There were 4,285 incident cancers in people with type 2 diabetes. RR for any cancers (adjusted for age only) was 1.11 (95% CI 1.05, 1.17) for men and 1.33 (1.28, 1.40) for women. Corresponding values after additional adjustment for socioeconomic status were 1.10 (1.04, 1.15) and 1.31 (1.25, 1.38), respectively. RRs for individual cancer sites varied markedly.
Conclusions/interpretation
Socioeconomic status was found to have little influence on the association between type 2 diabetes and cancer.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>23661106</pmid><doi>10.1007/s00125-013-2937-6</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Diabetologia, 2013-08, Vol.56 (8), p.1712-1715 |
| issn | 0012-186X 1432-0428 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4131139 |
| source | Springer Nature |
| subjects | Age Aged Biological and medical sciences Cancer Diabetes Diabetes Mellitus, Type 2 - epidemiology Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Epidemiology Etiopathogenesis. Screening. Investigations. Target tissue resistance Female Human Physiology Humans Information services Internal Medicine Investigations Male Medical sciences Medicine Medicine & Public Health Metabolic Diseases Middle Aged Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Neoplasms - epidemiology Population Prostate Registration Scotland - epidemiology Short Communication Social Class Socioeconomic factors Tumors |
| title | Type 2 diabetes, socioeconomic status and risk of cancer in Scotland 2001–2007 |
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