The optical, photothermal, and facile surface chemical properties of gold and silver nanoparticles in biodiagnostics, therapy, and drug delivery

Nanotechnology is a rapidly growing area of research in part due to its integration into many biomedical applications. Within nanotechnology, gold and silver nanostructures are some of the most heavily utilized nanomaterial due to their unique optical, photothermal, and facile surface chemical prope...

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Bibliographic Details
Published in:Archives of toxicology 2014-07, Vol.88 (7), p.1391-1417
Main Authors: Austin, Lauren A., Mackey, Megan A., Dreaden, Erik C., El-Sayed, Mostafa A.
Format: Article
Language:English
Subjects:
Animals
Biomedical and Life Sciences
Biomedical engineering
Biomedical materials
Biomedicine
Chemical properties
Diagnostic Imaging - methods
Drug delivery
Drug Delivery Systems
Environmental Health
Gold
Gold - chemistry
Humans
Metal Nanoparticles
Nanomaterials
Nanoparticles
Nanostructure
Nanotechnology
Nanotechnology - methods
Occupational Medicine/Industrial Medicine
Optical properties
Pharmacology/Toxicology
Review Article
Silver
Silver - chemistry
Toxicology
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Summary:Nanotechnology is a rapidly growing area of research in part due to its integration into many biomedical applications. Within nanotechnology, gold and silver nanostructures are some of the most heavily utilized nanomaterial due to their unique optical, photothermal, and facile surface chemical properties. In this review, common colloid synthesis methods and biofunctionalization strategies of gold and silver nanostructures are highlighted. Their unique properties are also discussed in terms of their use in biodiagnostic, imaging, therapeutic, and drug delivery applications. Furthermore, relevant clinical applications utilizing gold and silver nanostructures are also presented. We also provide a table with reviews covering related topics.
ISSN:0340-5761
1432-0738
DOI:10.1007/s00204-014-1245-3