Impact of Seasons and Dioecy on Therapeutic Phytoconstituents of Tinospora cordifolia, a Rasayana Drug

Tinospora cordifolia (Thunb.) Miers, Menispermaceae, is a dioecious creeper, commonly known as “Giloe” or “Guduchi” with significant medicinal importance in the traditional systems of medicine. It is designated as Rasayana drug in Ayurveda and recommended for a number of diseases and also as adaptog...

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Bibliographic Details
Published in:BioMed research international 2014-01, Vol.2014 (2014), p.1-11
Main Authors: Choudhry, Namrta, Singh, Shweta, Siddiqui, Mohammad Badruzzaman, Khatoon, Sayyada
Format: Article
Language:English
Subjects:
Antioxidants
Antioxidants - analysis
Ayurvedic medicine
Cancer
Care and treatment
Diabetes
Enzymes
Gender
Health aspects
Herbal medicine
India
Materia medica, Vegetable
Menispermaceae
Metabolites
Pharmacology, Experimental
Phytochemicals
Phytochemistry
Plant extracts
Plant Extracts - analysis
Plant Extracts - chemistry
Plant sciences
Plant Stems - chemistry
Plants, Medicinal - chemistry
Seasons
Sex Characteristics
Studies
Tinospora
Tinospora - chemistry
Wind
Winter
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Summary:Tinospora cordifolia (Thunb.) Miers, Menispermaceae, is a dioecious creeper, commonly known as “Giloe” or “Guduchi” with significant medicinal importance in the traditional systems of medicine. It is designated as Rasayana drug in Ayurveda and recommended for a number of diseases and also as adaptogen and immunomodulator. The safety and efficacy of herbal medicines are closely correlated with the quality of the source materials. The aim of this study is to see the effect of seasons on phytoconstituents and how these vary in male and female stem samples of T. cordifolia. The study revealed that total phenolics and total sugar concentration obtained highest values in summer season while starch and tannin content were found maximum in winter season in both the genders. However, biomarkers, tinosporaside and berberine, reached to their highest concentration in monsoon season. Further, antioxidant potential revealed the highest inhibition percentage in winter season as well as in late summer season. The results of this study suggest that the female plant is best for its therapeutic phytoconstituents and the best harvesting seasons may be either winter or late summer for antioxidant potential and immunomodulator activities and monsoon for antidiabetic activity of T. cordifolia.
ISSN:2314-6133
2314-6141
DOI:10.1155/2014/902138