Synthesis and Radioluminescence of PEGylated Eu3+-doped Nanophosphors as Bioimaging Probes

Lanthanide‐doped nanophosphors stimu­lated by high‐energy photons or β+‐particles display characteristic 590, 615, and 692 nm emissions of the Eu3+ activator. These radioluminescent nanophosphors, produced by a thermo degradation process and coated with poly(ethylene glycol), serve as imaging probes...

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2011-06, Vol.23 (24), p.H195-H199
Main Authors: Sun, Conroy, Pratx, Guillem, Carpenter, Colin M., Liu, Hongguang, Cheng, Zhen, Gambhir, Sanjiv Sam, Xing, Lei
Format: Article
Language:English
Subjects:
biomedical applications
bionanotechnology
lanthanide doping
luminescence
surface modification
Online Access:Get full text
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Summary:Lanthanide‐doped nanophosphors stimu­lated by high‐energy photons or β+‐particles display characteristic 590, 615, and 692 nm emissions of the Eu3+ activator. These radioluminescent nanophosphors, produced by a thermo degradation process and coated with poly(ethylene glycol), serve as imaging probes as demonstrated in vivo with matrigel inclusions detected by both a custom X‐ray luminescence and a conventional small animal optical imaging system.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201100919