Short mucin 1 alleles are associated with low virulent H pylori strains infection

TO THE EDITOR We read with interest the article published by Nguyen et al in the World Journal of Gastroenterology, showing an association between short MUC6 alleles and H pjloff infection. These results, together with previous observations by Vinall et al, reinforce the role of mucin genes （MUC6 an...

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Bibliographic Details
Published in:World journal of gastroenterology : WJG 2007-03, Vol.13 (12), p.1885-1886
Main Authors: Peleteiro, Barbara, Lunet, Nuno, Santos-Silva, Filipe, David, Leonor, Figueiredo, Céu, Barros, Henrique
Format: Article
Language:English
Subjects:
Alleles
Antigens, Neoplasm - genetics
Genetic Predisposition to Disease
Genotype
Helicobacter Infections - genetics
Helicobacter pylori - pathogenicity
Humans
Letters To The Editor
Mucin-1
Mucins - genetics
Polymorphism, Genetic
Virulence
低毒力幽门螺杆菌感染
相关性
短粘蛋白1
等位基因
遗传多态性
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Summary:TO THE EDITOR We read with interest the article published by Nguyen et al in the World Journal of Gastroenterology, showing an association between short MUC6 alleles and H pjloff infection. These results, together with previous observations by Vinall et al, reinforce the role of mucin genes （MUC6 and MUC1） VNTR polymorphisms for the variability in individual susceptibility to H pylori infection that cannot be explained by differences in environmental factors.
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v13.i12.1885