Sizing up Surfactant Synthesis

Phosphatidylcholine is generated through de novo synthesis and remodeling involving a lysophospholipid. In this issue of Cell Metabolism, research from the Shimizu lab (Harayama et al., 2014) demonstrates the highly selective enzymatic behavior of lysophospholipid acyltransferases. The authors prese...

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Bibliographic Details
Published in:Cell metabolism 2014-08, Vol.20 (2), p.195-196
Main Authors: Han, SeungHye, Mallampalli, Rama K.
Format: Article
Language:English
Subjects:
1-Acylglycerophosphocholine O-Acyltransferase - metabolism
Animals
Phosphatidylcholines - metabolism
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Summary:Phosphatidylcholine is generated through de novo synthesis and remodeling involving a lysophospholipid. In this issue of Cell Metabolism, research from the Shimizu lab (Harayama et al., 2014) demonstrates the highly selective enzymatic behavior of lysophospholipid acyltransferases. The authors present an enzymatic model for phosphatidylcholine molecular species diversification that impacts surfactant formation.
ISSN:1550-4131
1932-7420
DOI:10.1016/j.cmet.2014.07.015