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Sizing up Surfactant Synthesis

Phosphatidylcholine is generated through de novo synthesis and remodeling involving a lysophospholipid. In this issue of Cell Metabolism, research from the Shimizu lab (Harayama et al., 2014) demonstrates the highly selective enzymatic behavior of lysophospholipid acyltransferases. The authors prese...

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Published in:Cell metabolism 2014-08, Vol.20 (2), p.195-196
Main Authors: Han, SeungHye, Mallampalli, Rama K.
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description Phosphatidylcholine is generated through de novo synthesis and remodeling involving a lysophospholipid. In this issue of Cell Metabolism, research from the Shimizu lab (Harayama et al., 2014) demonstrates the highly selective enzymatic behavior of lysophospholipid acyltransferases. The authors present an enzymatic model for phosphatidylcholine molecular species diversification that impacts surfactant formation.
doi_str_mv 10.1016/j.cmet.2014.07.015
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source BACON - Elsevier - GLOBAL_SCIENCEDIRECT-OPENACCESS
subjects 1-Acylglycerophosphocholine O-Acyltransferase - metabolism
Animals
Phosphatidylcholines - metabolism
title Sizing up Surfactant Synthesis
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