Early Glottic Cancer : Role of MRI in the Preoperative Staging

Introduction. Clinical staging is the most important time in management of glottic cancer in early stage (I-II). We have conducted a prospective study to evaluate if magnetic resonance imaging (MRI) is more accurate than computed tomography (CT) about tumoral extension, to exactly choose the most ap...

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Bibliographic Details
Published in:BioMed research international 2014-01, Vol.2014 (2014), p.1-7
Main Authors: Ferrise, Pierpaolo, Allegra, Eugenia, Trapasso, Serena, Trapuzzano, Orazio, Barca, Antonio, Tamburrini, Stefania, Garozzo, Aldo
Format: Article
Language:English
Subjects:
Aged
Biomedical research
Care and treatment
Diagnosis
Glottis
Health aspects
Humans
Laryngeal cancer
Laryngeal Neoplasms - diagnostic imaging
Laryngeal Neoplasms - pathology
Laryngeal Neoplasms - surgery
Magnetic Resonance Imaging
Male
Methods
Middle Aged
Neoplasm Staging
Preoperative Care
Statistics as Topic
Tomography, X-Ray Computed
Vocal Cords - diagnostic imaging
Vocal Cords - pathology
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Summary:Introduction. Clinical staging is the most important time in management of glottic cancer in early stage (I-II). We have conducted a prospective study to evaluate if magnetic resonance imaging (MRI) is more accurate than computed tomography (CT) about tumoral extension, to exactly choose the most appropriate surgical approach, from organ preservation surgery to demolitive surgery. Materials and Methods. This prospective study was conducted on 26 male patients, with suspected laryngeal neoplasia of glottic region. The images of MRI and CT were analyzed to define the expansion of glottic lesion to anterior commissure, laryngeal cartilages, subglottic and/or supraglottic site, and paraglottic space. The results of MRI and CT were compared with each other and with the pathology report. Results. CT accuracy was 70% with low sensitivity but with high specific value. MRI showed a diagnostic accuracy in 80% of cases, with a sensitivity of 100% and high specificity. Statistical analysis showed that MRI has higher correlation than CT with the pathology report. Conclusion. Our study showed that MRI is more sensitive than CT in the preoperative staging of early glottic cancer, to select exactly the eligible patients in conservative surgery of the larynx, as supracricoid laryngectomy and cordectomy by CO2 laser.
ISSN:2314-6133
2314-6141
DOI:10.1155/2014/890385