Usefulness of 11C-methionine positron emission tomography for detecting intracranial ameloblastic carcinoma: A case report

Ameloblastic carcinoma, secondary type, is an extremely rare odontogenic malignant tumor. The present study reports the case of a 58-year-old male with ameloblastic carcinoma that extended into the intracranial space close to the internal carotid artery. Surgical excision was performed, as headaches...

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Bibliographic Details
Published in:Oncology letters 2014-10, Vol.8 (4), p.1509-1512
Main Authors: TEMPAKU, AKIRA, TAKAHASHI, YOSHINOBU, IKEDA, HIDETOSHI, YAMAUCHI, SHIGERU, GOTOH, TAKASHI, BANDOH, NOBUYUKI, MAKINO, SYUJIROU, SHIMADA, TAKUJI, KAMADA, HAJIME
Format: Article
Language:English
Subjects:
ameloblastic carcinoma
Carotid arteries
Case reports
intracranial extension
Metastasis
methionine-labeled positron emission tomography
Nervous system
NMR
Nuclear magnetic resonance
Protein synthesis
Proteins
Studies
Tumors
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Summary:Ameloblastic carcinoma, secondary type, is an extremely rare odontogenic malignant tumor. The present study reports the case of a 58-year-old male with ameloblastic carcinoma that extended into the intracranial space close to the internal carotid artery. Surgical excision was performed, as headaches were being caused via compression by the mass. Small remnants of the tumor remained surrounding the internal carotid artery following surgical resection. Although the remnant tissue was not detected on magnetic resonance imaging or 18F-fluorodeoxyglucose (FDG)-positron emission tomography (PET), it was clearly visualized on 11C-methionine PET in the early post-operative follow-up period. No neurological deficits were exhibited during the follow-up period, and 11C-methionine PET was able to detect the remnant lesion distribution in the intracranial space. The current study presents a rare case of ameloblastic carcinoma that extended into the intracranial space. In addition, several diagnostic imaging tools were compared in order to determine the most suitable imaging modality. At present, the patient is continuing a therapeutic course of radiation and evident mass reduction has been observed. However, the therapeutic effects are currently under consideration. To the best of our knowledge, this is the first study on the effectiveness of using 11C-methionine PET for detecting ameloblastic carcinoma with intracranial extension.
ISSN:1792-1074
1792-1082
DOI:10.3892/ol.2014.2352