Quantitative Comparison and Metabolite Profiling of Saponins in Different Parts of the Root of Panax notoginseng

Although both rhizome and root of Panax notoginseng are officially utilized as notoginseng in “Chinese Pharmacopoeia”, individual parts of the root were differently used in practice. To provide chemical evidence for the differentiated usage, quantitative comparison and metabolite profiling of differ...

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Bibliographic Details
Published in:Journal of agricultural and food chemistry 2014-09, Vol.62 (36), p.9024-9034
Main Authors: Wang, Jing-Rong, Yau, Lee-Fong, Gao, Wei-Na, Liu, Yong, Yick, Pui-Wing, Liu, Liang, Jiang, Zhi-Hong
Format: Article
Language:English
Subjects:
Chromatography, High Pressure Liquid
Ginsenosides - analysis
metabolites
Metabolomics
multivariate analysis
Panax notoginseng
Panax notoginseng - chemistry
Plant Roots - chemistry
Reproducibility of Results
Rhizome - chemistry
rhizomes
saponins
Saponins - analysis
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Summary:Although both rhizome and root of Panax notoginseng are officially utilized as notoginseng in “Chinese Pharmacopoeia”, individual parts of the root were differently used in practice. To provide chemical evidence for the differentiated usage, quantitative comparison and metabolite profiling of different portions derived from the whole root, as well as commercial samples, were carried out, showing an overall higher content of saponins in rhizome, followed by main root, branch root, and fibrous root. Ginsenoside Rb2 was proposed as a potential marker with a content of 0.5 mg/g as a threshold value for differentiating rhizome from other parts. Multivariate analysis of the metabolite profile further suggested 32 saponins as potential markers for the discrimination of different parts of notoginseng. Collectively, the study provided comprehensive chemical evidence for the distinct usage of different parts of notoginseng and, hence, is of great importance for the rational application and exploitation of individual parts of notoginseng.
ISSN:0021-8561
1520-5118
DOI:10.1021/jf502214x