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Perspective for Prophylaxis and Treatment of Cervical Cancer: An Immunological Approach
As the second most common cause of cancer-related death in women, human papilloma virus (HPV) vaccines have been a major step in decreasing the morbidity and mortality associated with cervical cancer. An estimated 490,000 women are diagnosed with cervical cancer each year. Increasing knowledge of th...
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Published in: | International Reviews of Immunology 2012-02, Vol.31 (1), p.3-21 |
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container_title | International Reviews of Immunology |
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creator | Jenkins, Marjorie Chiriva-Internati, Maurizio Mirandola, Leonardo Tonroy, Catherine Tedjarati, Sean S. Davis, Nicole D'Cunha, Nicholas Tijani, Lukman Hardwick, Fred Nguyen, Diane Kast, W. Martin Cobos, Everardo |
description | As the second most common cause of cancer-related death in women, human papilloma virus (HPV) vaccines have been a major step in decreasing the morbidity and mortality associated with cervical cancer. An estimated 490,000 women are diagnosed with cervical cancer each year. Increasing knowledge of the HPV role in the etiology of cervical cancer has led to the development and introduction of HPV-based vaccines for active immunotherapy of cervical cancer. Immunotherapies directed at preventing HPV-persistent infections. These vaccines are already accessible for prophylaxis and in the near future, they will be available for the treatment of preexisting HPV-related neoplastic lesions. |
doi_str_mv | 10.3109/08830185.2011.637254 |
format | article |
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Martin</creatorcontrib><creatorcontrib>Cobos, Everardo</creatorcontrib><title>Perspective for Prophylaxis and Treatment of Cervical Cancer: An Immunological Approach</title><title>International Reviews of Immunology</title><addtitle>Int Rev Immunol</addtitle><description>As the second most common cause of cancer-related death in women, human papilloma virus (HPV) vaccines have been a major step in decreasing the morbidity and mortality associated with cervical cancer. An estimated 490,000 women are diagnosed with cervical cancer each year. Increasing knowledge of the HPV role in the etiology of cervical cancer has led to the development and introduction of HPV-based vaccines for active immunotherapy of cervical cancer. Immunotherapies directed at preventing HPV-persistent infections. These vaccines are already accessible for prophylaxis and in the near future, they will be available for the treatment of preexisting HPV-related neoplastic lesions.</description><subject>Alphapapillomavirus - immunology</subject><subject>Animals</subject><subject>cancer vaccines</subject><subject>Carcinoma - prevention & control</subject><subject>Carcinoma - therapy</subject><subject>Cell Transformation, Neoplastic</subject><subject>Cell Transformation, Viral</subject><subject>Female</subject><subject>gynecologic oncology</subject><subject>HPV</subject><subject>Humans</subject><subject>immunotherapy</subject><subject>Immunotherapy, Active</subject><subject>Papillomavirus Infections - prevention & control</subject><subject>Papillomavirus Vaccines - therapeutic use</subject><subject>Sexually Transmitted Diseases, Viral - complications</subject><subject>Sexually Transmitted Diseases, Viral - prevention & control</subject><subject>Sexually Transmitted Diseases, Viral - virology</subject><subject>tumor prevention</subject><subject>Uterine Cervical Neoplasms - prevention & control</subject><subject>Uterine Cervical Neoplasms - therapy</subject><issn>0883-0185</issn><issn>1937-4364</issn><issn>1563-5244</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNp9kMtOwzAQRS0EglL4A4T8Ayl2_EjDAlRVPCoh0UURS8s4NglK4miSFvr3OJRWsOlqpJl778wchC4oGTFK0isyHjNCx2IUE0pHkiWx4AdoQFOWRJxJfogGvSTqNSfotG0_CKFMpPwYncRxLCghYoBe5xbaxpquWFnsPOA5-CZfl_qraLGuM7wAq7vK1h32Dk8trAqjSzzVtbFwjSc1nlXVsvalf_8ZTJoGvDb5GTpyumzt-W8dopf7u8X0MXp6fphNJ0-REXTcRakRMrZWckmkM0KQjJssIYwKk2QmDn9YmXLGdUIcd6HPw5c6CzLrKJcpG6KbTW6zfKtsZsKhoEvVQFFpWCuvC_V_Uhe5evcrxankMRUhgG8CDPi2Bet2XkpUD1ptQasetNqADrbLv3t3pi3ZILjdCIo6YK30p4cyU51elx4cBHxF28fvXXHzLyG3uuxyo8GqD7-EOmDdf-M3TNmhTw</recordid><startdate>20120201</startdate><enddate>20120201</enddate><creator>Jenkins, Marjorie</creator><creator>Chiriva-Internati, Maurizio</creator><creator>Mirandola, Leonardo</creator><creator>Tonroy, Catherine</creator><creator>Tedjarati, Sean S.</creator><creator>Davis, Nicole</creator><creator>D'Cunha, Nicholas</creator><creator>Tijani, Lukman</creator><creator>Hardwick, Fred</creator><creator>Nguyen, Diane</creator><creator>Kast, W. 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Martin</au><au>Cobos, Everardo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Perspective for Prophylaxis and Treatment of Cervical Cancer: An Immunological Approach</atitle><jtitle>International Reviews of Immunology</jtitle><addtitle>Int Rev Immunol</addtitle><date>2012-02-01</date><risdate>2012</risdate><volume>31</volume><issue>1</issue><spage>3</spage><epage>21</epage><pages>3-21</pages><issn>0883-0185</issn><eissn>1937-4364</eissn><eissn>1563-5244</eissn><abstract>As the second most common cause of cancer-related death in women, human papilloma virus (HPV) vaccines have been a major step in decreasing the morbidity and mortality associated with cervical cancer. An estimated 490,000 women are diagnosed with cervical cancer each year. Increasing knowledge of the HPV role in the etiology of cervical cancer has led to the development and introduction of HPV-based vaccines for active immunotherapy of cervical cancer. Immunotherapies directed at preventing HPV-persistent infections. These vaccines are already accessible for prophylaxis and in the near future, they will be available for the treatment of preexisting HPV-related neoplastic lesions.</abstract><cop>England</cop><pub>Informa Healthcare</pub><pmid>22251005</pmid><doi>10.3109/08830185.2011.637254</doi><tpages>19</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Alphapapillomavirus - immunology Animals cancer vaccines Carcinoma - prevention & control Carcinoma - therapy Cell Transformation, Neoplastic Cell Transformation, Viral Female gynecologic oncology HPV Humans immunotherapy Immunotherapy, Active Papillomavirus Infections - prevention & control Papillomavirus Vaccines - therapeutic use Sexually Transmitted Diseases, Viral - complications Sexually Transmitted Diseases, Viral - prevention & control Sexually Transmitted Diseases, Viral - virology tumor prevention Uterine Cervical Neoplasms - prevention & control Uterine Cervical Neoplasms - therapy |
title | Perspective for Prophylaxis and Treatment of Cervical Cancer: An Immunological Approach |
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