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Differences between pediatric extra-pulmonary and pulmonary tuberculosis: a warning sign for the future
Tuberculosis (TB) remains a major global health problem. The childhood tuberculosis has some unique features different which makes the diagnosis more complicated. Here we described the epidemiologic, clinical and microbiologic features of children with extra pulmonary and pulmonary TB. The data of t...
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Published in: | Mediterranean journal of hematology and infectious diseases 2014-01, Vol.6 (1), p.e2014058-e2014058 |
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container_title | Mediterranean journal of hematology and infectious diseases |
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creator | Devrim, Ilker Aktürk, Hüseyin Bayram, Nuri Apa, Hurşit Tulumoğlu, Sener Devrim, Fatma Erdem, Tülin Gulfidan, Gamze Ayhan, Yüce Tamsel, Ipek Can, Demet Alper, Hüdaver |
description | Tuberculosis (TB) remains a major global health problem. The childhood tuberculosis has some unique features different which makes the diagnosis more complicated. Here we described the epidemiologic, clinical and microbiologic features of children with extra pulmonary and pulmonary TB.
The data of the patients 10 years. PTB was present in 75,0% of the cases, and EXPTB was present in 25% of cases. There was no significant difference between the EXPTB and PTB by means of distribution of age groups (p=0,201). The rate of patients free of constitutional symptoms were significantly higher in EXPTB compared to PTB(p=0,000). There was no significant difference between EXPTB and PTB by means of sources detection(p=0,069).
TB is still a major public health problem. EXPTB has an insidious and silent onset without any constitutional symptoms, and both microbiological confirmation and the source by an adult are not frequently found. Moreover, detection of the adult source is mandatory for controlling the TB disease in children. |
doi_str_mv | 10.4084/MJHID.2014.058 |
format | article |
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The data of the patients <14 years with active TB were collected and compared in pulmonary (PTB) and extrapulmonary TB (EXPTB) patients.
A total of 128 cases was included. Forty-two cases occurred in children were < 5 years of age; 41 cases between 6-10 years and 45 cases > 10 years. PTB was present in 75,0% of the cases, and EXPTB was present in 25% of cases. There was no significant difference between the EXPTB and PTB by means of distribution of age groups (p=0,201). The rate of patients free of constitutional symptoms were significantly higher in EXPTB compared to PTB(p=0,000). There was no significant difference between EXPTB and PTB by means of sources detection(p=0,069).
TB is still a major public health problem. EXPTB has an insidious and silent onset without any constitutional symptoms, and both microbiological confirmation and the source by an adult are not frequently found. Moreover, detection of the adult source is mandatory for controlling the TB disease in children.</description><identifier>ISSN: 2035-3006</identifier><identifier>EISSN: 2035-3006</identifier><identifier>DOI: 10.4084/MJHID.2014.058</identifier><identifier>PMID: 25237471</identifier><language>eng</language><publisher>Italy: Università Cattolica del Sacro Cuore</publisher><subject>Original</subject><ispartof>Mediterranean journal of hematology and infectious diseases, 2014-01, Vol.6 (1), p.e2014058-e2014058</ispartof><rights>2014</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165496/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165496/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25237471$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Devrim, Ilker</creatorcontrib><creatorcontrib>Aktürk, Hüseyin</creatorcontrib><creatorcontrib>Bayram, Nuri</creatorcontrib><creatorcontrib>Apa, Hurşit</creatorcontrib><creatorcontrib>Tulumoğlu, Sener</creatorcontrib><creatorcontrib>Devrim, Fatma</creatorcontrib><creatorcontrib>Erdem, Tülin</creatorcontrib><creatorcontrib>Gulfidan, Gamze</creatorcontrib><creatorcontrib>Ayhan, Yüce</creatorcontrib><creatorcontrib>Tamsel, Ipek</creatorcontrib><creatorcontrib>Can, Demet</creatorcontrib><creatorcontrib>Alper, Hüdaver</creatorcontrib><title>Differences between pediatric extra-pulmonary and pulmonary tuberculosis: a warning sign for the future</title><title>Mediterranean journal of hematology and infectious diseases</title><addtitle>Mediterr J Hematol Infect Dis</addtitle><description>Tuberculosis (TB) remains a major global health problem. The childhood tuberculosis has some unique features different which makes the diagnosis more complicated. Here we described the epidemiologic, clinical and microbiologic features of children with extra pulmonary and pulmonary TB.
The data of the patients <14 years with active TB were collected and compared in pulmonary (PTB) and extrapulmonary TB (EXPTB) patients.
A total of 128 cases was included. Forty-two cases occurred in children were < 5 years of age; 41 cases between 6-10 years and 45 cases > 10 years. PTB was present in 75,0% of the cases, and EXPTB was present in 25% of cases. There was no significant difference between the EXPTB and PTB by means of distribution of age groups (p=0,201). The rate of patients free of constitutional symptoms were significantly higher in EXPTB compared to PTB(p=0,000). There was no significant difference between EXPTB and PTB by means of sources detection(p=0,069).
TB is still a major public health problem. EXPTB has an insidious and silent onset without any constitutional symptoms, and both microbiological confirmation and the source by an adult are not frequently found. Moreover, detection of the adult source is mandatory for controlling the TB disease in children.</description><subject>Original</subject><issn>2035-3006</issn><issn>2035-3006</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNpVUE1PwzAMjRCITWNXjihHLh1J03yUAxLagA0NcYFzlabuFtSlJWkZ_HuKGDB8sJ9l671nI3RKySQhKrl4uJ8vZpOY0GRCuDpAw5gwHjFCxOEeHqBxCC-kD8aoYvExGsQ8ZjKRdIhWM1uW4MEZCDiHdgvgcAOF1a23BsN763XUdNWmdtp_YO0K_Ne1XQ7edFUdbLjEGm-1d9atcLArh8va43YNuOzazsMJOip1FWC8qyP0fHvzNJ1Hy8e7xfR6GTWxEG0kdZ5wwVIq8hQEFVRyA7npM5OSaFVoyiSjuWIFy0nMFaTKyIIraUgs0pSN0NU3b9PlGygMuP6AKmu83fSOs1rb7P_E2XW2qt-yhAqepKInON8R-Pq1g9BmGxsMVJV2UHcho1_2lJKc9qtn-1q_Ij_fZZ-SeH8I</recordid><startdate>20140101</startdate><enddate>20140101</enddate><creator>Devrim, Ilker</creator><creator>Aktürk, Hüseyin</creator><creator>Bayram, Nuri</creator><creator>Apa, Hurşit</creator><creator>Tulumoğlu, Sener</creator><creator>Devrim, Fatma</creator><creator>Erdem, Tülin</creator><creator>Gulfidan, Gamze</creator><creator>Ayhan, Yüce</creator><creator>Tamsel, Ipek</creator><creator>Can, Demet</creator><creator>Alper, Hüdaver</creator><general>Università Cattolica del Sacro Cuore</general><scope>NPM</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20140101</creationdate><title>Differences between pediatric extra-pulmonary and pulmonary tuberculosis: a warning sign for the future</title><author>Devrim, Ilker ; Aktürk, Hüseyin ; Bayram, Nuri ; Apa, Hurşit ; Tulumoğlu, Sener ; Devrim, Fatma ; Erdem, Tülin ; Gulfidan, Gamze ; Ayhan, Yüce ; Tamsel, Ipek ; Can, Demet ; Alper, Hüdaver</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p266t-7ab4563916b9e616175cebc75c3770a8da13731b83d3b0258e98c7d587c026993</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Original</topic><toplevel>online_resources</toplevel><creatorcontrib>Devrim, Ilker</creatorcontrib><creatorcontrib>Aktürk, Hüseyin</creatorcontrib><creatorcontrib>Bayram, Nuri</creatorcontrib><creatorcontrib>Apa, Hurşit</creatorcontrib><creatorcontrib>Tulumoğlu, Sener</creatorcontrib><creatorcontrib>Devrim, Fatma</creatorcontrib><creatorcontrib>Erdem, Tülin</creatorcontrib><creatorcontrib>Gulfidan, Gamze</creatorcontrib><creatorcontrib>Ayhan, Yüce</creatorcontrib><creatorcontrib>Tamsel, Ipek</creatorcontrib><creatorcontrib>Can, Demet</creatorcontrib><creatorcontrib>Alper, Hüdaver</creatorcontrib><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Mediterranean journal of hematology and infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Devrim, Ilker</au><au>Aktürk, Hüseyin</au><au>Bayram, Nuri</au><au>Apa, Hurşit</au><au>Tulumoğlu, Sener</au><au>Devrim, Fatma</au><au>Erdem, Tülin</au><au>Gulfidan, Gamze</au><au>Ayhan, Yüce</au><au>Tamsel, Ipek</au><au>Can, Demet</au><au>Alper, Hüdaver</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Differences between pediatric extra-pulmonary and pulmonary tuberculosis: a warning sign for the future</atitle><jtitle>Mediterranean journal of hematology and infectious diseases</jtitle><addtitle>Mediterr J Hematol Infect Dis</addtitle><date>2014-01-01</date><risdate>2014</risdate><volume>6</volume><issue>1</issue><spage>e2014058</spage><epage>e2014058</epage><pages>e2014058-e2014058</pages><issn>2035-3006</issn><eissn>2035-3006</eissn><abstract>Tuberculosis (TB) remains a major global health problem. The childhood tuberculosis has some unique features different which makes the diagnosis more complicated. Here we described the epidemiologic, clinical and microbiologic features of children with extra pulmonary and pulmonary TB.
The data of the patients <14 years with active TB were collected and compared in pulmonary (PTB) and extrapulmonary TB (EXPTB) patients.
A total of 128 cases was included. Forty-two cases occurred in children were < 5 years of age; 41 cases between 6-10 years and 45 cases > 10 years. PTB was present in 75,0% of the cases, and EXPTB was present in 25% of cases. There was no significant difference between the EXPTB and PTB by means of distribution of age groups (p=0,201). The rate of patients free of constitutional symptoms were significantly higher in EXPTB compared to PTB(p=0,000). There was no significant difference between EXPTB and PTB by means of sources detection(p=0,069).
TB is still a major public health problem. EXPTB has an insidious and silent onset without any constitutional symptoms, and both microbiological confirmation and the source by an adult are not frequently found. Moreover, detection of the adult source is mandatory for controlling the TB disease in children.</abstract><cop>Italy</cop><pub>Università Cattolica del Sacro Cuore</pub><pmid>25237471</pmid><doi>10.4084/MJHID.2014.058</doi><oa>free_for_read</oa></addata></record> |
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title | Differences between pediatric extra-pulmonary and pulmonary tuberculosis: a warning sign for the future |
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