Role of interventional therapy in hepatic artery stenosis and non-anastomosis bile duct stricture after orthotopic liver transplantation

To analyze the clinical manifestations and the effectiveness of therapy in patients with orthotopic liver transplantation (OLT)-associated hepatic artery stenosis (HAS) and non-anastomosis bile duct stricture. Nine cases were diagnosed as HAS and non-anastomosis bile duct stricture. Percutaneous tra...

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Published in:World journal of gastroenterology : WJG 2007-06, Vol.13 (22), p.3128-3132
Main Authors: Zhao, Da-Bing, Shan, Hong, Jiang, Zai-Bo, Huang, Ming-Sheng, Zhu, Kang-Shun, Chen, Gui-Hua, Meng, Xiao-Chun, Guan, Shou-Hai, Li, Zheng-Ran, Qian, Jie-Sheng
Format: Article
Language:English
Subjects:
Adult
Aged
Angioplasty, Balloon - methods
Catheterization - methods
Cholestasis - etiology
Cholestasis - surgery
Cholestasis - therapy
Constriction, Pathologic - complications
Constriction, Pathologic - etiology
Female
Hepatic Artery - surgery
Humans
Liver Transplantation - adverse effects
Male
Middle Aged
Rapid Communication
Reperfusion Injury - complications
Reperfusion Injury - etiology
Retrospective Studies
Stents
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Summary:To analyze the clinical manifestations and the effectiveness of therapy in patients with orthotopic liver transplantation (OLT)-associated hepatic artery stenosis (HAS) and non-anastomosis bile duct stricture. Nine cases were diagnosed as HAS and non-anastomosis bile duct stricture. Percutaneous transluminal angioplasty (PTA) was performed in four HAS cases, and expectant treatment in other five HAS cases; percutaneous transhepatic bile drainage, balloon dilation, stent placement were performed in all nine cases. Diffuse intra- and extra-bile duct stricture was observed in nine cases, which was associated with bile mud siltation and biliary infection. Obstruction of the bile duct was improved obviously or removed. Life span/follow-up period was 13-30 mo after PTA of four HAS cases, 6-23 mo without PTA of other five cases. Progressive, non-anastomosis, and diffuse bile duct stricture are the characteristic manifestations of HAS and non-anastomosis bile duct stricture after OLT. These are often associated with bile mud siltation, biliary infection, and ultimate liver failure. Interventional therapy is significantly beneficial.
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v13.i22.3128