Sleep duration is associated with white matter hyperintensity volume in older adults: the Northern Manhattan Study

Summary Self‐reports of long or short sleep durations have indicated an association with cardiovascular morbidity and mortality, but there are limited data evaluating their association with white matter hyperintensity volume (WMHV), a marker of cerebral small vessel disease. We conducted a cross‐sec...

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Bibliographic Details
Published in:Journal of sleep research 2014-10, Vol.23 (5), p.524-530
Main Authors: Ramos, Alberto R., Dong, Chuanhui, Rundek, Tatjana, Elkind, Mitchell S. V., Boden‐Albala, Bernadette, Sacco, Ralph L., Wright, Clinton B.
Format: Article
Language:English
Subjects:
Adult
Aged
Aging - pathology
Cohort Studies
diabetes
Diabetes Mellitus - epidemiology
Diabetes Mellitus - pathology
elderly
Female
Hispanic Americans
Humans
hyperintensities
leukoaraiosis
long sleep
Magnetic Resonance Imaging
Male
Middle Aged
multi‐ethnic
New York City - epidemiology
Prevalence
Risk Factors
Self Report
short sleep
Sleep - physiology
Stroke
Time Factors
white matter
White Matter - pathology
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Summary:Summary Self‐reports of long or short sleep durations have indicated an association with cardiovascular morbidity and mortality, but there are limited data evaluating their association with white matter hyperintensity volume (WMHV), a marker of cerebral small vessel disease. We conducted a cross‐sectional analysis of self‐reported sleep duration to test for a correlation with white matter hyperintensities, measured by quantitative magnetic resonance imaging (MRI), in the Northern Manhattan Study. We used multivariable linear regression models to assess associations between both short (
ISSN:0962-1105
1365-2869
DOI:10.1111/jsr.12177