Is there a role for colon capsule endoscopy beyond colorectal cancer screening? A literature review

Colon capsule endoscopy is recommended in Europe alternatively to colonoscopy for colorectal cancer screening in average risk individuals. The procedure has also been proposed to complete colon examination in cases of incomplete colonoscopy or when colonoscopy is contraindicated or refused by the pa...

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Bibliographic Details
Published in:World journal of gastroenterology : WJG 2014-09, Vol.20 (36), p.13006-13014
Main Authors: Triantafyllou, Konstantinos, Beintaris, Iosif, Dimitriadis, George D
Format: Article
Language:English
Subjects:
Capsule
Capsule Endoscopy
Colitis, Ulcerative - pathology
Colitis, Ulcerative - therapy
Colon
Colon - pathology
Colonoscopy
Colorectal Neoplasms - pathology
Early Detection of Cancer - methods
endoscopy
Humans
Incomplete
Intestinal Mucosa - pathology
Predictive Value of Tests
Prognosis
Severity of Illness Index
Topic Highlight
Ulc
Wound Healing
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Summary:Colon capsule endoscopy is recommended in Europe alternatively to colonoscopy for colorectal cancer screening in average risk individuals. The procedure has also been proposed to complete colon examination in cases of incomplete colonoscopy or when colonoscopy is contraindicated or refused by the patient. As tissue samples cannot be obtained with the current capsule device, colon capsule endoscopy has no place in diagnosing ulcerative colitis or in dysplasia surveillance. Nevertheless, data are accumulating regarding its feasibility to examine ulcerative colitis disease extent and to monitor disease activity and mucosal healing, even though reported results on the capsule’s performance in this field vary greatly. In this review we present the currently available evidence for the use of colon capsule endoscopy to complement colonoscopy failure to reach the cecum and its use to evaluate ulcerative colitis disease activity and extent. Moreover, we provide an outlook on issues requiring further investigation before the capsule becomes a mainstream alternative to colonoscopy in such cases.
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v20.i36.13006