Clinical features of coronary artery ectasia in the elderly

• Published in: Journal of geriatric cardiology : JGC 2014-09, Vol.11 (3), p.185-191
• Main Authors: Huang, Qiao-Juan, Zhang, Yan, Li, Xiao-Lin, Li, Sha, Guo, Yuan-Lin, Zhu, Cheng-Gang, Xu, Rui-Xia, Jiang, Li-Xin, Chen, Meng-Hua, Li, Jian-Jun
• Format: Article
• Language: English
• Subjects: CAE; 中老年人; 临床特征; 临床特点; 冠状动脉造影; 成像特性; 生存曲线; 质量指数
• ISSN: 1671-5411
• DOI: 10.11909/j.issn.1671-5411.2014.03.012

Objective To investigate the incidence, imaging and clinical characteristics in elderly patients with coronary artery ectasia （CAE）. Methods A retrospective analysis was conducted on patients with CAE who underwent coronary angiography between January 2006 and December 2012. According to age, the enrolled patients were divided into two groups （elderly group, age≥ 65 years; non-elderly group, age 〈 65 years）. The clinical feature, imaging characteristics and the 5-year survival rate of the two groups were compared.Results The preva-lence of CAE in elderly patients was 0.33%. Patients in elderly group were found to have significantly higher proportion of female （30.1%vs. 10.1%,P〈 0.001）, three-vessel disease （60.5%vs. 45.2%,P = 0.003） and localized ectasia （55.0%vs. 40.2%,P = 0.003）. In addition, body mass index （20.90 ± 2.71 kg/m2vs. 22.31 ± 2.98 kg/m2,P 〈 0.001） and percentage of current smokers （45.0%vs. 64.6%,P 〈 0.001） were significantly lower in elderly group. Cumulative survival curves demonstrated reduced 5-year cumulative survival at the follow-up in the elderly group compared with the non-elderly group （88.0%vs. 96.0%,P = 0.002）. But the 5-year event free survival rate failed to show a significant difference between the two groups （31.0%vs. 35.0%,P= 0.311）.ConclusionThe prevalence of CAE in elderly patients was 0.33%, which was about 1/3 of the entire numbers of CAE patients. There were significant differences between the elderly and the non-elderly patients with CAE in terms of coronary artery disease risk factors and coronary artery ectatic characteristics. CAE might be asso-ciated with increased mortality risk in the elderly.