Orbital rhabdomyosarcoma with skin metastasis: a case report

Rhabdomyosarcoma is a soft tissue neoplasm that usually arises in the head and neck region and genitourinary tract. Skin metastasis of rhabdomyosarcoma is extremely rare; of thirteen cases reported in the literature, most were children younger than 10 years and only three cases have been reported in...

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Bibliographic Details
Published in:BMC research notes 2014-09, Vol.7 (1), p.670-670, Article 670
Main Authors: Elomrani, Fadwa, Touri, Salima, Ouziane, Imane, Berrada, Narjiss, Boutayeb, Saber, Mrabti, Hind, Elkhannoussi, Basma, Errihani, Hassan
Format: Article
Language:English
Subjects:
Biomarkers, Tumor - analysis
Biopsy
Care and treatment
Case Report
Chemoradiotherapy, Adjuvant
Chemotherapy, Adjuvant
Diagnosis
Humans
Immunohistochemistry
Male
Metastasis
Neoplasm Recurrence, Local
Ophthalmologic Surgical Procedures
Orbital Neoplasms - chemistry
Orbital Neoplasms - pathology
Orbital Neoplasms - therapy
Patient outcomes
Radiotherapy
Reoperation
Rhabdomyosarcoma, Embryonal - chemistry
Rhabdomyosarcoma, Embryonal - secondary
Rhabdomyosarcoma, Embryonal - therapy
Skin Neoplasms - chemistry
Skin Neoplasms - secondary
Skin Neoplasms - therapy
Time Factors
Treatment Outcome
Young Adult
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Summary:Rhabdomyosarcoma is a soft tissue neoplasm that usually arises in the head and neck region and genitourinary tract. Skin metastasis of rhabdomyosarcoma is extremely rare; of thirteen cases reported in the literature, most were children younger than 10 years and only three cases have been reported in adults. A 20-year-old Moroccan man was admitted with a right orbital tumor. The tumor was excised and histopathology examination confirmed a diagnosis of rhabdomyosarcoma. The patient was treated with chemotherapy, but local recurrence occurred one year later. The patient underwent right orbital exenteration followed by chemotherapy and radiotherapy. After 6 months, the patient developed a cutaneous mass in the right lumbar region, which was resected. Immunohistochemical examination of the tumor showed this to be a cutaneous metastasis of rhabdomyosarcoma. The patient was treated by chemotherapy and there appeared to be no recurrence after 9 months of follow up. Skin metastasis from rhabdomyosarcoma is extremely rare, particularly in adults. The purpose of presenting this case report is to raise awareness among clinicians--skin biopsy and immunohistochemistry are needed to distinguish this neoplasm from other cutaneous tumors so that appropriate treatment can be initiated.
ISSN:1756-0500
1756-0500
DOI:10.1186/1756-0500-7-670