Anthelmintic resistance in sheep gastrointestinal nematodes in Slovakia detected by in-vitro methods

• Published in: BMC veterinary research 2014-10, Vol.10 (1), p.233-233, Article 233
• Main Authors: Dolinská, Michaela, Ivanišinová, Oksana, Königová, Alžbeta, Várady, Marián
• Format: Article
• Language: English
• Subjects: Animals; anthelmintics; Anthelmintics - therapeutic use; benzimidazole; Benzimidazoles - therapeutic use; Drug dosages; Drug Resistance; Eggs; farmers; farms; Gastrointestinal Diseases - drug therapy; Gastrointestinal Diseases - parasitology; Gastrointestinal Diseases - veterinary; gastrointestinal nematodes; hatching; Health aspects; Infection control; Ivermectin - therapeutic use; Laboratories; Methods; Nematoda; Nematode Infections - drug therapy; Nematode Infections - epidemiology; Nematode Infections - veterinary; Parasites; Parasitic Sensitivity Tests; Physiological aspects; Sheep; Sheep - parasitology; Sheep Diseases - drug therapy; Sheep Diseases - epidemiology; Sheep Diseases - parasitology; Slovakia; Slovakia - epidemiology; Studies; Surveys; Yeast
• ISSN: 1746-6148; 1746-6148
• DOI: 10.1186/s12917-014-0233-4

BACKGROUND: The intensive use of anthelmintics for the control of helminthic infections has resulted in the development of anthelmintic resistance, which has become a major practical problem in many countries. A variety of tests are available to monitor anthelmintic resistance but most of them are expensive, laborious and time consuming and therefore unpractical for large field surveys. The main aim of this survey was thus to detect the occurrence of benzimidazole (BZ) and macrocyclic lactone resistance on sheep farms in Slovakia by using novel and modified in vitro methods that are inexpensive, easy to use and quick and therefore practical for large surveys. RESULTS: BZ-resistant gastrointestinal nematodes were found on all 27 farms. Two farms (7.4%) had high levels of resistance (>40% of hatching), and 22 farms had low levels (