Lumbar discitis caused by Clostridium perfringens

We report here a rare case of chronic lumbar discitis caused by Clostridium perfringens in an elderly patient that was treated with a combination of β-lactams and clindamycin. Molecular analysis performed on the strain revealed an unusual toxin gene pattern.

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Bibliographic Details
Published in:Journal of clinical microbiology 2014-10, Vol.52 (10), p.3813-3815
Main Authors: Lotte, Romain, Popoff, M R, Degand, Nicolas, Lotte, Laurene, Bouvet, Philippe, Baudin, Guillaume, Cua, Eric, Roger, Pierre-Marie, Ruimy, Raymond
Format: Article
Language:English
Subjects:
Aged, 80 and over
Anti-Bacterial Agents
Anti-Bacterial Agents - pharmacology
Anti-Bacterial Agents - therapeutic use
Bacterial Toxins
Bacterial Toxins - genetics
beta-Lactams
beta-Lactams - therapeutic use
Case Reports
Clindamycin
Clindamycin - therapeutic use
Clostridium Infections
Clostridium Infections - diagnosis
Clostridium Infections - drug therapy
Clostridium Infections - microbiology
Clostridium Infections - pathology
Clostridium perfringens
Clostridium perfringens - genetics
Clostridium perfringens - isolation & purification
Discitis
Discitis - diagnosis
Discitis - drug therapy
Discitis - microbiology
Discitis - pathology
Female
Genotype
Humans
Intervertebral Disc Degeneration
Intervertebral Disc Degeneration - diagnosis
Intervertebral Disc Degeneration - drug therapy
Intervertebral Disc Degeneration - microbiology
Intervertebral Disc Degeneration - pathology
Intervertebral Disc Displacement
Intervertebral Disc Displacement - diagnosis
Intervertebral Disc Displacement - drug therapy
Intervertebral Disc Displacement - microbiology
Intervertebral Disc Displacement - pathology
Life Sciences
Microbial Sensitivity Tests
Polymerase Chain Reaction
Spine
Spine - diagnostic imaging
Spine - pathology
Tomography, X-Ray Computed
Toxicology
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Description
Summary:We report here a rare case of chronic lumbar discitis caused by Clostridium perfringens in an elderly patient that was treated with a combination of β-lactams and clindamycin. Molecular analysis performed on the strain revealed an unusual toxin gene pattern.
ISSN:0095-1137
1098-660X
DOI:10.1128/JCM.00983-14