Are effector memory T cells the key to an effective HIV/AIDS vaccine?
Graphical Abstract Tried and true vaccine approaches to HIV have failed. Could Cytomegalovirus and its “goldilocks” level of viral persistence maintain robust, “effector memory” T‐cell responses and finally produce an effective, early‐intervention vaccine against HIV?
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Published in: | EMBO reports 2014-08, Vol.15 (8), p.820-821 |
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description | Graphical Abstract
Tried and true vaccine approaches to HIV have failed. Could Cytomegalovirus and its “goldilocks” level of viral persistence maintain robust, “effector memory” T‐cell responses and finally produce an effective, early‐intervention vaccine against HIV? |
doi_str_mv | 10.15252/embr.201439052 |
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Tried and true vaccine approaches to HIV have failed. Could Cytomegalovirus and its “goldilocks” level of viral persistence maintain robust, “effector memory” T‐cell responses and finally produce an effective, early‐intervention vaccine against HIV?</description><subject>AIDS Vaccines</subject><subject>Animals</subject><subject>EMBO19</subject><subject>EMBO52</subject><subject>HIV - immunology</subject><subject>HIV Infections - prevention & control</subject><subject>Humans</subject><subject>Immunologic Memory</subject><subject>Opinion</subject><subject>T-Lymphocyte Subsets</subject><issn>1469-221X</issn><issn>1469-3178</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNqFkc1vEzEQxVcIREvhzA1Z4sJlG48_dzmAQhvaQCkSlMDN8jqz7bb70dqbQP57HDZEAQlx8kj-vTdv9JLkKdBDkEyyETaFP2QUBM-pZPeSfRAqTzno7P5mZgy-7SWPQrimlMpcZw-TPSbyjGZK7SeTsUeCZYmu7zxpsOn8ilwQh3UdSH-F5AZXpO-IbTdUtURyOp2NxtPjz2RpnatafP04eVDaOuCTzXuQfHk7uTg6Tc8-nkyPxmepkxJYCrmzBWfRBzIKDjiWVBSijBOfUylUocCC5UpnKIGyGH9eaGtVocFKrfhB8mrwvV0UDc4dtr23tbn1VWP9ynS2Mn_-tNWVueyWRkCuKV8bvNgY-O5ugaE3TRXWx9oWu0UwINd7dUZpRJ__hV53C9_G8wxoKTMtdCYiNRoo57sQPJbbMEDNr4rMuiKzrSgqnu3esOV_dxKBlwPwvapx9T8_M_nw5tOuOx3EIeraS_Q7qf8ZKB0kVejxx3af9TdGaa6l-Xp-Yt7N3mvG9cyc85_vOrq7</recordid><startdate>201408</startdate><enddate>201408</enddate><creator>Picker, Louis J</creator><general>Blackwell Publishing Ltd</general><general>Nature Publishing Group UK</general><general>Springer Nature B.V</general><general>BlackWell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7T5</scope><scope>7TM</scope><scope>7TO</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>201408</creationdate><title>Are effector memory T cells the key to an effective HIV/AIDS vaccine?</title><author>Picker, Louis J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5512-19cab32ffe1801c13ef04b4fc133d0546b61a1a3678e5102469db7aa6b71a5763</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>AIDS Vaccines</topic><topic>Animals</topic><topic>EMBO19</topic><topic>EMBO52</topic><topic>HIV - immunology</topic><topic>HIV Infections - prevention & control</topic><topic>Humans</topic><topic>Immunologic Memory</topic><topic>Opinion</topic><topic>T-Lymphocyte Subsets</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Picker, Louis J</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Immunology Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>EMBO reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Picker, Louis J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Are effector memory T cells the key to an effective HIV/AIDS vaccine?</atitle><jtitle>EMBO reports</jtitle><stitle>EMBO Rep</stitle><addtitle>EMBO rep</addtitle><date>2014-08</date><risdate>2014</risdate><volume>15</volume><issue>8</issue><spage>820</spage><epage>821</epage><pages>820-821</pages><issn>1469-221X</issn><eissn>1469-3178</eissn><coden>ERMEAX</coden><abstract>Graphical Abstract
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source | Open Access: PubMed Central |
subjects | AIDS Vaccines Animals EMBO19 EMBO52 HIV - immunology HIV Infections - prevention & control Humans Immunologic Memory Opinion T-Lymphocyte Subsets |
title | Are effector memory T cells the key to an effective HIV/AIDS vaccine? |
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