Abnormalities in Cu and Zn levels in acute hepatitis of different etiologies

Copper (Cu) and Zinc (Zn) are essential trace elements which play an important role in various biological processes. Zn deficiency is common in liver diseases while Cu deficiency is rarely reported. To determine whether serum Cu and Zn concentrations differed in acute hepatitis, compared to controls...

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Published in:Hippokratia 2014-01, Vol.18 (2), p.144-149
Main Authors: Papanikolopoulos, K, Alexopoulou, A, Dona, A, Hadziyanni, E, Vasilieva, L, Dourakis, S
Format: Article
Language:English
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Summary:Copper (Cu) and Zinc (Zn) are essential trace elements which play an important role in various biological processes. Zn deficiency is common in liver diseases while Cu deficiency is rarely reported. To determine whether serum Cu and Zn concentrations differed in acute hepatitis, compared to controls and investigate possible correlations of Cu and Zn values with etiology and severity of liver diseases. Serum Cu and Zn concentrations were determined by air acetylene flame atomic absorption spectrometer in 40 patients (acute hepatitis A, B, C, autoimmune and drug induced hepatitis) and 150 healthy controls. Compared to healthy controls, significantly higher Zn levels were found in patients (106.5 μg/dl, P
ISSN:1108-4189
1790-8019