Novel strategies for managing pancreatic cancer

With the incidence reports of pancreatic cancer increasing every year,research over the last several decades has been focused on the means to achieve early diagnosis in patients that are at a high risk of developing the malignancy.This review covers current strategies for managing pancreatic cancer...

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Bibliographic Details
Published in:World journal of gastroenterology : WJG 2014-10, Vol.20 (40), p.14717-14725
Main Authors: Loc, Welley S, Smith, Jill P, Matters, Gail, Kester, Mark, Adair, James H
Format: Article
Language:English
Subjects:
Animals
Antineoplastic Agents - therapeutic use
Biomarkers, Tumor - blood
Biomarkers, Tumor - genetics
cancer
Diagnosis
Drug Resistance, Neoplasm
Early Detection of Cancer - trends
Genetic Markers
Genetic Predisposition to Disease
Genetic Testing - trends
Humans
Mutation
Nanomedicine - trends
Pancreatic
Pancreatic Neoplasms - blood
Pancreatic Neoplasms - genetics
Pancreatic Neoplasms - mortality
Pancreatic Neoplasms - pathology
Pancreatic Neoplasms - therapy
Phenotype
Predictive Value of Tests
Risk Factors
Signal Transduction
Signaling
Topic Highlight
Treatment
Treatment Outcome
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Summary:With the incidence reports of pancreatic cancer increasing every year,research over the last several decades has been focused on the means to achieve early diagnosis in patients that are at a high risk of developing the malignancy.This review covers current strategies for managing pancreatic cancer and further discusses efforts in understanding the role of early onset symp-toms leading to tumor progression.Recent investigations in this discussion include type 3c diabetes,selected biomarkers and pathways related to pancreatic intraepithelial neoplasia lesions,drug resistance,and advances in nanomedicine which may provide significant solutions for improving early detection and treatments in future medicine.
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v20.i40.14717