The prevalence of hypertension and abnormal kidney function in children with sickle cell disease -a cross sectional review

Renal disease is a known contributor to mortality in adults with sickle cell disease (SCD) and renal abnormalities are evident in childhood. Hyperfiltration (evidenced by elevated glomerular filtration rate, GFR) occurs in children with SCD early in disease. However, the incidence of low GFR (

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Bibliographic Details
Published in:BMC nephrology 2013-10, Vol.14 (1), p.237-237, Article 237
Main Authors: Bodas, Prasad, Huang, Alex, O'Riordan, Mary Ann, Sedor, John R, Dell, Katherine MacRae
Format: Article
Language:English
Subjects:
Adolescent
Age
Age Distribution
Analysis
Anemia, Sickle Cell - epidemiology
Biomarkers
Child
Child, Preschool
Children
Children & youth
Chromatography
Clinical trials
Comorbidity
Complications and side effects
Cross-Sectional Studies
Female
Gender
Genotype & phenotype
Health aspects
Humans
Hypertension
Hypertension - epidemiology
Illnesses
Kidney diseases
Male
Medical research
Medicine, Experimental
Mortality
Nephrology
NMR
Nuclear magnetic resonance
Ohio - epidemiology
Pediatrics
Prevalence
Renal Insufficiency, Chronic - epidemiology
Retrospective Studies
Risk Factors
Sex Distribution
Sickle cell anemia
Sickle cell disease
Statistical analysis
Stroke (Disease)
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Description
Summary:Renal disease is a known contributor to mortality in adults with sickle cell disease (SCD) and renal abnormalities are evident in childhood. Hyperfiltration (evidenced by elevated glomerular filtration rate, GFR) occurs in children with SCD early in disease. However, the incidence of low GFR (
ISSN:1471-2369
1471-2369
DOI:10.1186/1471-2369-14-237