Slowing of EEG background activity in Parkinson's and Alzheimer's disease with early cognitive dysfunction

Slowing of the electroencephalogram (EEG) is frequent in Parkinson's (PD) and Alzheimer's disease (AD) and correlates with cognitive decline. As overlap pathology plays a role in the pathogenesis of dementia, it is likely that demented patients in PD show similar physiological alterations...

Full description

Saved in:
Bibliographic Details
Published in:Frontiers in aging neuroscience 2014-11, Vol.6, p.314-314
Main Authors: Benz, Nina, Hatz, Florian, Bousleiman, Habib, Ehrensperger, Michael M, Gschwandtner, Ute, Hardmeier, Martin, Ruegg, Stephan, Schindler, Christian, Zimmermann, Ronan, Monsch, Andreas Urs, Fuhr, Peter
Format: Article
Language:English
Subjects:
Activities of daily living
Aging
Alzheimer's disease
Cognitive ability
Dementia
Dementia disorders
Drug dosages
Education
EEG
Electrodes
Electroencephalography
Gender
Immunotherapy
Movement disorders
Neurodegenerative diseases
Neurology
Neuroscience
Parkinson's disease
Patients
Task forces
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Slowing of the electroencephalogram (EEG) is frequent in Parkinson's (PD) and Alzheimer's disease (AD) and correlates with cognitive decline. As overlap pathology plays a role in the pathogenesis of dementia, it is likely that demented patients in PD show similar physiological alterations as in AD. To analyze distinctive quantitative EEG characteristics in early cognitive dysfunction in PD and AD. Forty patients (20 PD- and 20 AD patients with early cognitive impairment) and 20 normal controls (NC) were matched for gender, age, and education. Resting state EEG was recorded from 256 electrodes. Relative power spectra, median frequency (4-14 Hz), and neuropsychological outcome were compared between groups. Relative theta power in left temporal region and median frequency separated the three groups significantly (p = 0.002 and p 
ISSN:1663-4365
1663-4365
DOI:10.3389/fnagi.2014.00314