Ophthalmological features of Parkinson disease

• Published in: Medical science monitor 2014-11, Vol.20, p.2243-2249
• Main Authors: Nowacka, Barbara, Lubinski, Wojciech, Honczarenko, Krystyna, Potemkowski, Andrzej, Safranow, Krzysztof
• Format: Article
• Language: English
• Subjects: Aged; Case-Control Studies; Clinical Research; Eye - pathology; Female; Glaucoma - complications; Glaucoma - pathology; Humans; Male; Parkinson Disease - complications; Parkinson Disease - pathology; Surveys and Questionnaires
• ISSN: 1643-3750; 1234-1010; 1643-3750
• DOI: 10.12659/MSM.890861

The aim of this study was to determine the type and frequency of ophthalmologic changes occurring in patients with Parkinson disease (PD). One hundred consecutive patients (196 eyes) with idiopathic PD and a control group consisting of 100 healthy patients (196 eyes) matched for age and sex underwent a complete ophthalmological examination of both eyes, including assessment of patient medical history, dry eye questionare, and visual hallucinations questionnaire, distance and near best corrected visual acuity (DBCVA, NBCVA), color vision, distance photopic contrast sensitivity, near point of convergence, slit lamp examination of the eye anterior segment, tear film osmolarity and breakup time, aqueous tear production, and intraocular pressure, as well as fundus examination and evaluation of the perimacular retinal thickness (RT) and peripapillary retinal nerve fiber layer (RNFL) thickness. In the eyes of PD patients DBCVA, NBCVA, contrast sensitivity, and color discrimination were significantly reduced. We also detected increased frequency of convergence insufficiency, seborrhoic blepharitis, meibomian gland disease (MGD), dry eye syndrome, nuclear and posterior subcapsular cataract, and glaucoma (p