Phenotypic and genetic heterogeneity among subjects with mild airflow obstruction in COPDGene

Summary Background Chronic obstructive pulmonary disease (COPD) is characterized by marked phenotypic heterogeneity. Most previous studies have focused on COPD subjects with FEV1  

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Bibliographic Details
Published in:Respiratory medicine 2014-10, Vol.108 (10), p.1469-1480
Main Authors: Lee, Jin Hwa, Cho, Michael H, McDonald, Merry-Lynn N, Hersh, Craig P, Castaldi, Peter J, Crapo, James D, Wan, Emily S, Dy, Jennifer G, Chang, Yale, Regan, Elizabeth A, Hardin, Megan, DeMeo, Dawn L, Silverman, Edwin K
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Chronic obstructive
Chronic obstructive pulmonary disease
Cigarettes
Cluster analysis
Emphysema
Epidemiology
Female
Forced Expiratory Volume - genetics
Genetic association
Genetic Predisposition to Disease
Genomes
Gold
Hispanic people
Humans
Male
Middle Aged
Mortality
Polymorphism, Single Nucleotide
Population characteristics
Pulmonary disease
Pulmonary Disease, Chronic Obstructive - complications
Pulmonary Disease, Chronic Obstructive - genetics
Pulmonary/Respiratory
Regression analysis
Risk Factors
Smoking
Smoking - epidemiology
Spirometry
Studies
Variables
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Description
Summary:Summary Background Chronic obstructive pulmonary disease (COPD) is characterized by marked phenotypic heterogeneity. Most previous studies have focused on COPD subjects with FEV1  
ISSN:0954-6111
1532-3064
DOI:10.1016/j.rmed.2014.07.018