Soft tissue sarcoma across the age spectrum: A population-based study from the surveillance epidemiology and end results database

Background Soft tissue sarcomas (STS) are a heterogeneous group of mesenchymal malignancies that occur throughout the lifespan. The impact of age on disease features and outcome is unclear. Methods We analyzed the clinical features and outcome of all STS cases registered between 1973 and 2006 in the...

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Bibliographic Details
Published in:Pediatric blood & cancer 2011-12, Vol.57 (6), p.943-949
Main Authors: Ferrari, Andrea, Sultan, Iyad, Huang, Tseng Tien, Rodriguez-Galindo, Carlos, Shehadeh, Ahmad, Meazza, Cristina, Ness, Kirsten K., Casanova, Michela, Spunt, Sheri L.
Format: Article
Language:English
Subjects:
Adolescent
Adult
age
Age Distribution
Age Factors
Aged
Child
Child, Preschool
Databases, Factual
epidemiology
Female
Humans
Infant
Infant, Newborn
Male
Middle Aged
prognosis
Rhabdomyosarcoma - diagnosis
Rhabdomyosarcoma - epidemiology
Sarcoma - diagnosis
Sarcoma - epidemiology
SEER
soft tissue sarcoma
Survival Analysis
Young Adult
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Summary:Background Soft tissue sarcomas (STS) are a heterogeneous group of mesenchymal malignancies that occur throughout the lifespan. The impact of age on disease features and outcome is unclear. Methods We analyzed the clinical features and outcome of all STS cases registered between 1973 and 2006 in the SEER database. Results There were 48,012 cases that met the selection criteria. Individuals less than 20 years of age represented 5.6%, with rhabdomyosarcoma being the most common subtype. In adults, the most common types were Kaposi sarcoma, fibrohistiocytic tumors, and leiomyosarcoma. Rhabdomyosarcoma was the only entity with a median age
ISSN:1545-5009
1545-5017
DOI:10.1002/pbc.23252