The effect of L-carnitine treatment on levels of malondialdehyde and glutathione in patients with age related macular degeneration

The aim of this study was to determine the antioxidant properties of the L-carnitine (LC) in the treatment of patients with age-related macular degeneration (AMD). This study involved 60 patients diagnosed with early AMD. The patients were divided into two groups. Group I was the study group that re...

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Bibliographic Details
Published in:The Eurasian journal of medicine 2008-04, Vol.40 (1), p.1-5
Main Authors: Ates, Orhan, Alp, H Hakan, Mumcu, Ugur, Azizi, Sedat, Cinici, Emine, Kiziltunc, Ahmet, Baykal, Orhan
Format: Article
Language:English
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Summary:The aim of this study was to determine the antioxidant properties of the L-carnitine (LC) in the treatment of patients with age-related macular degeneration (AMD). This study involved 60 patients diagnosed with early AMD. The patients were divided into two groups. Group I was the study group that received LC supplementation for 3 months. Group II was the control group and did not consent to LC supplementation over the 3 months. At the end of the 3-month period, markers of lipid peroxidation, malondialdehyde (MDA) and reduced glutathione (GSH) were measured in the two groups. In the study group, the MDA level was significantly reduced, while the GSH level was significantly increased at the end of the 3-month period (P
ISSN:1308-8734
1308-8742