Quantification of Asymptomatic Kidney Stone Burden by Computed Tomography for Predicting Future Symptomatic Stone Events

Objective To find the optimal characterization of asymptomatic radiographic stone burden on computed tomography (CT) scans. Methods A survey was sent to stone formers who underwent a CT scan while asymptomatic during a stone clinic evaluation. Symptomatic stone passage events after CT scan were dete...

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Bibliographic Details
Published in:Urology (Ridgewood, N.J.) N.J.), 2015-01, Vol.85 (1), p.45-50
Main Authors: Selby, Michael G, Vrtiska, Terri J, Krambeck, Amy E, McCollough, Cynthia H, Elsherbiny, Hisham E, Bergstralh, Eric J, Lieske, John C, Rule, Andrew D
Format: Article
Language:English
Subjects:
Asymptomatic Diseases
Female
Humans
Kidney Calculi - diagnostic imaging
Male
Middle Aged
Prognosis
Tomography, X-Ray Computed
Urology
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Summary:Objective To find the optimal characterization of asymptomatic radiographic stone burden on computed tomography (CT) scans. Methods A survey was sent to stone formers who underwent a CT scan while asymptomatic during a stone clinic evaluation. Symptomatic stone passage events after CT scan were detected by survey and medical record review. Radiographic stone burden was quantified by number of stones, largest stone diameter, automated total stone volume (TSV), and bilateral stones and then compared as predictors of stone events. Results There were 550 stone formers; 43% had a stone event for a median of 4.7 years after the CT scan. Stone burden by quartiles was 0-1, 2-3, 4-6, and ≥7 for number of stones; 0-2, 3-4, 5-7, and ≥8 mm for largest stone diameter; and 0-8, 9-78, 79-280, and ≥281 mm3 for TSV; 48% had bilateral stones. The hazard ratios (HRs) for symptomatic event was 1.30 ( P  
ISSN:0090-4295
1527-9995
DOI:10.1016/j.urology.2014.08.031