Application of joinpoint regression in determining breast cancer incidence rate change points by age and tumor characteristics in women aged 30-69 (years) and in Isfahan city from 2001 to 2010

• Published in: Journal of education and health promotion 2014, Vol.3, p.115
• Main Authors: Dehkordi, Zahra, Tazhibi, Mehdi, Babazade, Shadi
• Format: Article
• Language: English
• Subjects: African Americans; Age Groups; Attrition (Research Studies); Breast cancer; Cancer; Developed Nations; Disease Incidence; Females; Mammography; Original; Pacific Islanders; Program Evaluation; Regression (Statistics); Trend Analysis; Trends; Womens health
• ISSN: 2277-9531; 2319-6440
• DOI: 10.4103/2277-9531.145917

Background and Objectives: Breast cancer is a major threat to women's health. Evaluation of the changes in trend of the incidence rate provides valuable information for the assessment and planning of development indicators of each country. The aim of the present study was to apply the JoinPoint regression model for determining changes in the trend of the breast cancer incidence rate in Isfahan. Materials and Methods: In this cross-sectional study, 3640 women with breast cancer referring to oncology and radiotherapy departments of Seyed-al-Shohada and Milad cancer treatment centers of Isfahan during 2001-2010 were studied and sampling was not done. Joinpoint regression model was used to investigate the pattern of breast cancer incidence rate. Response and independent variables were the natural logarithm of the age-standardized incidence rates and year of diagnosis of breast cancer, respectively, in which various levels of cancer tumor characteristics (P < 0.05) were analyzed. Results: The incidence rates increased annually in the age groups of 40-44 years (6.2%), 45-49 years (5.3%), and 55-59 years (5.3%). The trend of incidence rates in women with tumor size