High-field MR imaging in pediatric congenital heart disease: Initial results

• Published in: Pediatric radiology 2015-01, Vol.45 (1), p.42-54
• Main Authors: Nguyen, Kim-Lien, Khan, Sarah N., Moriarty, John M., Mohajer, Kiyarash, Renella, Pierangelo, Satou, Gary, Ayad, Ihab, Patel, Swati, Boechat, M. Ines, Finn, J. Paul
• Format: Article
• Language: English
• Subjects: Child; Child, Preschool; Female; Heart Defects, Congenital - pathology; Humans; Image Enhancement - methods; Imaging; Infant; Infant, Newborn; Magnetic Resonance Angiography - methods; Magnetic Resonance Imaging, Cine - methods; Male; Medicine; Medicine & Public Health; Neuroradiology; Nuclear Medicine; Oncology; Original; Original Article; Pediatrics; Radiology; Reproducibility of Results; Sensitivity and Specificity; Ultrasound
• ISSN: 0301-0449; 1432-1998
• DOI: 10.1007/s00247-014-3093-y

Background Comprehensive assessment of pediatric congenital heart disease (CHD) at any field strength mandates evaluation of both vascular and dynamic cardiac anatomy for which diagnostic quality contrast-enhanced magnetic resonance angiography (CEMRA) and cardiac cine are crucial. Objective To determine whether high-resolution (HR) CEMRA and steady-state free precession (SSFP) cine can be performed reliably at 3.0 T in children with CHD and to compare the image quality to similar techniques performed at 1.5 T. Materials and methods Twenty-eight patients with a median age of 5 months and average weight 9.0 ± 7.8 kg with suspected or known CHD were evaluated at 3.0 T. SSFP cine ( n  = 86 series) and HR-CEMRA ( n  = 414 named vascular segments) were performed and images were scored for image quality and artifacts. The findings were compared to those of 28 patients with CHD of similar weight who were evaluated at 1.5 T. Results Overall image quality on HR-CEMRA was rated as excellent or good in 96% (397/414) of vascular segments at 3.0 T (k = 0.49) and in 94% (349/371) of vascular segments at 1.5 T (k = 0.36). Overall image quality of SSFP was rated excellent or good in 91% (78/86) of cine series at 3.0 T (k = 0.55) and in 81% (87/108) at 1.5 T (k = 0.47). Off-resonance artifact was common at both field strengths, varied over the cardiac cycle and was more prevalent at 3.0 T. At 3.0 T, off-resonance dark band artifact on SSFP cine was absent in 3% (3/86), mild in 69% (59/86), moderate in 27% (23/86) and severe in 1% (1/86) of images; at 1.5 T, dark band artifact was absent in 16% (17/108), mild in 69% (75/108), moderate in 12% (13/108) and severe in 3% (3/108) of cine images. The signal-to-noise ratio and contrast-to-noise ratio of both SSFP cine and HR-CEMRA images were significantly higher at 3.0 T than at 1.5 T ( P