Defining new surrogate markers for CKD progression

At a recent meeting of international experts on clinical aspects of progressive chronic kidney disease (CKD), an extensive analysis of extant clinical trials was used to develop more effective and economical surrogate markers for CKD outcomes in adults. This article describes the reasons for this un...

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Bibliographic Details
Published in:Pediatric nephrology (Berlin, West) West), 2015-02, Vol.30 (2), p.193-198
Main Authors: Schnaper, H. William, Furth, Susan L., Yao, Lynne P.
Format: Article
Language:English
Subjects:
Adult
Biological products
Biomarkers
Biomarkers - analysis
Child
Clinical trials
Creatinine
Diabetes
Diagnosis
Disease Progression
Editorial Commentary
FDA approval
Female
Glomerular Filtration Rate
Humans
Kidney diseases
Male
Medicine
Medicine & Public Health
Nephrology
Patient outcomes
Pediatrics
Renal Insufficiency, Chronic - drug therapy
Renal Insufficiency, Chronic - pathology
Treatment Outcome
Urology
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Summary:At a recent meeting of international experts on clinical aspects of progressive chronic kidney disease (CKD), an extensive analysis of extant clinical trials was used to develop more effective and economical surrogate markers for CKD outcomes in adults. This article describes the reasons for this undertaking, the methods and conclusions of the meeting, and the relevance of these findings to pediatric nephrology.
ISSN:0931-041X
1432-198X
DOI:10.1007/s00467-014-2995-0