New perspectives for investigating respiratory failure induced by cervical spinal cord injury

Traumatic cervical spinal cord injury （SCI）, with an annual incidence of 12,000 new cases in USA （NSCISC 2013）, causes devastating locomotor and respiratory paralysis and unfortunately compromises the human patient＇s lifespan. The severity of the injury depends on the degree and the extent of the in...

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Bibliographic Details
Published in:Neural regeneration research 2014-11, Vol.9 (22), p.1949-1951
Main Authors: Bonay, Marcel, Vinit, Stéphane
Format: Article
Language:English
Subjects:
Animals
Complications and side effects
Laboratories
Mortality
Neurophysiology
Neurosciences
Paralysis
Respiratory failure
Respiratory insufficiency
Risk factors
SCI
Spinal cord injuries
Studies
发病率
呼吸衰竭
外伤性
死亡率
脊髓损伤
自然恢复
颈髓
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Summary:Traumatic cervical spinal cord injury （SCI）, with an annual incidence of 12,000 new cases in USA （NSCISC 2013）, causes devastating locomotor and respiratory paralysis and unfortunately compromises the human patient＇s lifespan. The severity of the injury depends on the degree and the extent of the initial trauma. In fact, respiratory failure is the leading cause of mortality following upper cervical SCI. However, 80% of the injuries are incomplete, allowing some modest spontaneous recovery. To date, no effective treatment is available in order to restore the loss of function.
ISSN:1673-5374
1876-7958
DOI:10.4103/1673-5374.145367