Evaluation of spinal cord injury animal models

Because there is no curative treatment for spinal cord injury, establishing an ideal animal model is important to identify injury mechanisms and develop therapies for individuals suffering from spinal cord injuries. In this article, we systematically review and analyze various kinds of animal models...

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Bibliographic Details
Published in:Neural regeneration research 2014-11, Vol.9 (22), p.2008-2012
Main Authors: Zhang, Ning, Fang, Marong, Chen, Haohao, Gou, Fangming, Ding, Mingxing
Format: Article
Language:English
Subjects:
Academic Discussion
Analysis
Animal models in research
Animals
Clinical trials
Contusions
Developing countries
LDCs
Rodents
Spinal cord injuries
Studies
动物模型
脊髓损伤
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Summary:Because there is no curative treatment for spinal cord injury, establishing an ideal animal model is important to identify injury mechanisms and develop therapies for individuals suffering from spinal cord injuries. In this article, we systematically review and analyze various kinds of animal models of spinal cord injury and assess their advantages and disadvantages for further studies.
ISSN:1673-5374
1876-7958
DOI:10.4103/1673-5374.143436