Preoperative nutritional support in cancer patients with no clinical signs of malnutrition—prospective randomized controlled trial

Purpose Preoperative nutrition is beneficial for malnourished cancer patients. Yet, there is little evidence whether or not it should be given to nonmalnourished patients. The aim of this study was to assess the need to introduce preoperative nutritional support in patients without malnutrition at q...

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Bibliographic Details
Published in:Supportive care in cancer 2015-02, Vol.23 (2), p.365-370
Main Authors: Kabata, Paweł, Jastrzębski, Tomasz, Kąkol, Michał, Król, Karolina, Bobowicz, Maciej, Kosowska, Anna, Jaśkiewicz, Janusz
Format: Article
Language:English
Subjects:
Adult
Aged
Body weight
Cachexia - etiology
Cancer
Cancer patients
Clinical trials
Diet
Diet therapy
Dietary Supplements
Female
Gastrointestinal Neoplasms - complications
Gastrointestinal Neoplasms - surgery
Humans
Male
Malnutrition
Malnutrition - etiology
Medicine
Medicine & Public Health
Middle Aged
Nursing
Nursing Research
Nutrition
Nutritional Status
Nutritional Support - methods
Oncology
Original
Original Article
Pain Medicine
Postoperative Complications - prevention & control
Preoperative Care
Prospective Studies
Rehabilitation Medicine
Weight Loss
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Summary:Purpose Preoperative nutrition is beneficial for malnourished cancer patients. Yet, there is little evidence whether or not it should be given to nonmalnourished patients. The aim of this study was to assess the need to introduce preoperative nutritional support in patients without malnutrition at qualification for surgery. Methods This was a prospective, two-arm, randomized, controlled, open-label study. Patients in interventional group received nutritional supplementation for 14 days before surgery, while control group kept on to their everyday diet. Each patient’s nutritional status was assessed twice—at qualification (weight loss in 6 months, laboratory parameters: albumin, total protein, transferrin, and total lymphocyte count) and 1 day before surgery (change in body weight and laboratory parameters). After surgery, all patients were followed up for 30 days for postoperative complications. Results Fifty-four patients in interventional and 48 in control group were analyzed. In postoperative period, patients in control group suffered from significantly higher ( p  
ISSN:0941-4355
1433-7339
DOI:10.1007/s00520-014-2363-4