Liver inflammation is a risk factor for prediabetes in at-risk latinos with and without hepatitis C infection

Background & Aims Early recognition of prediabetes can lead to timely clinical interventions to prevent type 2 diabetes. Both Latino ethnicity and chronic hepatitis C (HCV) have been identified as diabetic risk factors. We aimed to investigate predictors of impaired fasting glucose (IFG), a comm...

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Bibliographic Details
Published in:Liver international 2015-01, Vol.35 (1), p.101-107
Main Authors: Burman, Blaire E., Bacchetti, Peter, Ayala, Claudia E., Gelman, Nicholas, Melgar, Jennifer, Khalili, Mandana
Format: Article
Language:English
Subjects:
Adult
ALT
Blood Glucose - metabolism
Female
Glucose Tolerance Test
HCV
Hepatitis - complications
Hepatitis C - complications
Hispanic Americans
hispanics
Humans
impaired fasting glucose
insulin resistance
Logistic Models
Male
Middle Aged
Odds Ratio
Prediabetic State - ethnology
Prediabetic State - etiology
Risk Factors
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Summary:Background & Aims Early recognition of prediabetes can lead to timely clinical interventions to prevent type 2 diabetes. Both Latino ethnicity and chronic hepatitis C (HCV) have been identified as diabetic risk factors. We aimed to investigate predictors of impaired fasting glucose (IFG), a common prediabetic state, among Latinos with and without HCV. Methods One hundred Latino adults with no history of diabetes or cirrhosis underwent clinical, laboratory, and metabolic evaluation, including oral glucose tolerance testing (OGTT) and insulin suppression testing to quantify directly measured insulin resistance (IR). Isolated IFG was defined as fasting glucose ≥100 mg/dl and
ISSN:1478-3223
1478-3231
DOI:10.1111/liv.12676