Perinatal factors associated with early neonatal deaths in very low birth weight preterm infants in Northeast Brazil

In Brazil, the prevalence of prematurity has increased in recent years and it is a major cause of death in the neonatal period. Therefore, this study aims at assessing perinatal factors associated with early neonatal deaths in very low birth weight preterm infants born in a region of Brazil with low...

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Bibliographic Details
Published in:BMC pediatrics 2014-12, Vol.14 (1), p.312-312, Article 312
Main Authors: Castro, Eveline Campos Monteiro de, Leite, Álvaro Jorge Madeiro, Almeida, Maria Fernanda Branco de, Guinsburg, Ruth
Format: Article
Language:English
Subjects:
Analysis
Babies
Birth Weight
Brazil - epidemiology
Female
Gestational Age
Health aspects
Hospitals
Humans
Infant
Infant Mortality
Infant, Newborn
Infant, Very Low Birth Weight
Infants
Infants (Premature)
Male
Neonatal care
Patient outcomes
Perinatal Care - standards
Pregnancy
Pregnancy, Multiple
Prospective Studies
Pulmonary Surfactants - therapeutic use
Retrospective Studies
Sex Factors
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Summary:In Brazil, the prevalence of prematurity has increased in recent years and it is a major cause of death in the neonatal period. Therefore, this study aims at assessing perinatal factors associated with early neonatal deaths in very low birth weight preterm infants born in a region of Brazil with low Human Development Index. Prospective cohort study of inborns with gestational age 23(0/7)-31(6/7) weeks and birthweight 500-1499 g without malformations in 19 public reference hospitals of the state capitals of Brazil's Northeast Region. Perinatal variables associated with early neonatal death were determined by Cox regression analysis. Among 627 neonates, 179 (29%) died with 0-6 days after birth. Early death was associated to: absence of antenatal steroids (HR 1.59; 95% CI 1.11-2.27), multiple gestation (1.95; 1.28-3.00), male sex (2.01; 1.40-2.86), 5th minute Apgar
ISSN:1471-2431
1471-2431
DOI:10.1186/s12887-014-0312-5