Reliability of Noninvasive Assessment of Systolic Pulmonary Artery Pressure by Doppler Echocardiography Compared to Right Heart Catheterization: Analysis in a Large Patient Population

Background Pulmonary artery pressure (PAP) is an important marker in cardiovascular disorders, being closely associated with morbidity and mortality. Noninvasive assessment by Doppler echocardiography is recommended by current guidelines. So far, the reliability of this method has been assessed only...

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Bibliographic Details
Published in:Journal of the American Heart Association 2014-08, Vol.3 (4), p.n/a
Main Authors: Greiner, Sebastian, Jud, Andreas, Aurich, Matthias, Hess, Alexander, Hilbel, Thomas, Hardt, Stefan, Katus, Hugo A., Mereles, Derliz
Format: Article
Language:English
Subjects:
Aged
Cardiac Catheterization
Doppler echocardiography
Echocardiography, Doppler
Female
Humans
Hypertension, Pulmonary - diagnosis
Hypertension, Pulmonary - physiopathology
Male
Middle Aged
Original Research
Pulmonary Artery - physiology
Pulmonary Artery - physiopathology
pulmonary artery pressure
pulmonary hypertension
Pulmonary Wedge Pressure
Reproducibility of Results
Retrospective Studies
right heart catheterization
Systole
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Summary:Background Pulmonary artery pressure (PAP) is an important marker in cardiovascular disorders, being closely associated with morbidity and mortality. Noninvasive assessment by Doppler echocardiography is recommended by current guidelines. So far, the reliability of this method has been assessed only in small studies with contradictory results. Therefore, the aim of this study was to analyze the reliability of noninvasive PAP assessment by Doppler echocardiography compared to invasive measurements in a large patient population. Methods and Results We retrospectively analyzed data from a large tertiary cardiology department over 6 years in order to compare invasively measured PAP to estimated PAP from echocardiography examinations. N=15 516 patients fulfilled inclusion criteria and n=1695 patients with timely matched examinations (within 5 days) were analyzed. In n=1221 (72%) patients, pulmonary hypertension (PH) was diagnosed invasively (postcapillary PH: n=1122 [66%]; precapillary PH: n=99 [6%]). Systolic pulmonary artery pressure (sPAP) was 45.3±15.5 mm Hg by Doppler echocardiography and 47.4±16.4 mm Hg by right heart catheterization. Pearson's correlation coefficient was r=0.87 (P
ISSN:2047-9980
2047-9980
DOI:10.1161/JAHA.114.001103