Renal denervation of the native kidneys for drug-resistant hypertension after kidney transplantation

There is a strong rationale for renal denervation (RDN) of the native kidneys in kidney transplant recipients with treatment-resistant hypertension. We present a patient with a stable graft function, who underwent RDN for posttransplant therapy-resistant hypertension (24-h ambulatory blood pressure...

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Published in:Clinical kidney journal 2015-02, Vol.8 (1), p.79-81
Main Authors: Dobrowolski, Linn C., Bemelman, Frederike J., ten Berge, Ineke J.M., van den Born, Bert-Jan H., Reekers, Jim A., Krediet, C.T. Paul
Format: Article
Language:English
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Summary:There is a strong rationale for renal denervation (RDN) of the native kidneys in kidney transplant recipients with treatment-resistant hypertension. We present a patient with a stable graft function, who underwent RDN for posttransplant therapy-resistant hypertension (24-h ambulatory blood pressure measurement (ABPM) 143/89 mmHg, while compliantly using five different antihypertensive agents). After RDN, BP measurements and orthostatic complaints required withdrawal of two antihypertensive agents and halving a third. At 6 months, ABPM was 134/84 mmHg and allograft function remained unchanged. This case calls for designing well-designed prospective studies on RDN in kidney transplant recipients.
ISSN:2048-8505
2048-8513
DOI:10.1093/ckj/sfu134