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Concurrent peritonsillar abscess and poststreptococcal reactive arthritis complicating acute streptococcal tonsillitis in a young healthy adult: a case report
Streptococcus pyogenes is responsible for 5-15% and 20-30% of acute pharyngitis/tonsillitis in adults and children, respectively. It not only causes acute illness but also can give rise to local suppurative complications such as peritonsillar abscess as well as trigger the postinfectious syndromes o...
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Published in: | BMC infectious diseases 2015-02, Vol.15 (1), p.50-50, Article 50 |
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description | Streptococcus pyogenes is responsible for 5-15% and 20-30% of acute pharyngitis/tonsillitis in adults and children, respectively. It not only causes acute illness but also can give rise to local suppurative complications such as peritonsillar abscess as well as trigger the postinfectious syndromes of glomerulonephritis, acute rheumatic fever and poststreptococcal reactive arthritis. Here, we report a case of a young healthy adult in whom both peritonsillar abscess and poststreptococcal reactive arthritis developed as a complication of acute streptococcal tonsillitis. To the best of our knowledge, such a coincidence of poststreptococcal sequelae has not been reported previously.
A 32-year-old previously healthy woman was diagnosed with acute tonsillitis by her family doctor and treated empirically with amoxicillin/clavulanic acid (875/125 mg) twice daily for 5 days. Four days after completing antibiotic therapy, peritonsillar abscess of left tonsil developed. Needle aspiration followed by incision and drainage were performed by otolaryngologist at the Emergency Department. Next, the patient was discharged home on a 10-day course of cefuroxime and metronidazole. The symptoms of peritonsillar abscess were subsiding during treatment, however on the last day of antibiotic therapy, swelling and pain of the left ankle appeared. Five days later the patient was consulted by rheumatologist. Cultures of throat swabs and abscess aspirate collected 2 weeks before revealed the presence of Streptococcus pyogenes. Antistreptolysin O (ASO) titer was evaluated and proved to be 412 IU/ml (normal 0-200 IU/ml). The level of C-reactive protein was 13,0 mg/L (normal |
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A 32-year-old previously healthy woman was diagnosed with acute tonsillitis by her family doctor and treated empirically with amoxicillin/clavulanic acid (875/125 mg) twice daily for 5 days. Four days after completing antibiotic therapy, peritonsillar abscess of left tonsil developed. Needle aspiration followed by incision and drainage were performed by otolaryngologist at the Emergency Department. Next, the patient was discharged home on a 10-day course of cefuroxime and metronidazole. The symptoms of peritonsillar abscess were subsiding during treatment, however on the last day of antibiotic therapy, swelling and pain of the left ankle appeared. Five days later the patient was consulted by rheumatologist. Cultures of throat swabs and abscess aspirate collected 2 weeks before revealed the presence of Streptococcus pyogenes. Antistreptolysin O (ASO) titer was evaluated and proved to be 412 IU/ml (normal 0-200 IU/ml). The level of C-reactive protein was 13,0 mg/L (normal <5,0 mg/L). There was no known cardiac involvement. Poststreptococcal reactive arthritis was diagnosed. Left ankle arthralgia persisted for about 5-6 weeks. Six months after the presentation at the Emergency Department, the patient was well, with ASO titer reaching 262 IU/ml.
Clinicians should be aware that appropriate choice of antibiotic, proper dose as well as duration of therapy of acute GAS pharyngitis/tonsillitis are crucial to prevent poststreptococcal sequelae.</description><identifier>ISSN: 1471-2334</identifier><identifier>EISSN: 1471-2334</identifier><identifier>DOI: 10.1186/s12879-015-0780-8</identifier><identifier>PMID: 25885601</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Acute Disease ; Adult ; Arthritis, Infectious ; Arthritis, Reactive - diagnosis ; Arthritis, Reactive - microbiology ; Care and treatment ; Case Report ; Case studies ; Diagnosis ; Family medicine ; Female ; Health aspects ; Humans ; Infectious arthritis ; Patient outcomes ; Peritonsillar Abscess - diagnosis ; Peritonsillar Abscess - microbiology ; Pharyngitis - diagnosis ; Pharyngitis - microbiology ; Scarlet Fever - complications ; Scarlet Fever - diagnosis ; Streptococcal Infections - complications ; Streptococcus pyogenes - isolation & purification</subject><ispartof>BMC infectious diseases, 2015-02, Vol.15 (1), p.50-50, Article 50</ispartof><rights>COPYRIGHT 2015 BioMed Central Ltd.</rights><rights>Mazur et al.; licensee BioMed Central. 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b665t-16330374371224ece8dad923fa045151ad47ff51affb812000aefac94db073f13</citedby><cites>FETCH-LOGICAL-b665t-16330374371224ece8dad923fa045151ad47ff51affb812000aefac94db073f13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327960/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327960/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,37013,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25885601$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mazur, Elżbieta</creatorcontrib><creatorcontrib>Czerwińska, Ewa</creatorcontrib><creatorcontrib>Grochowalska, Aneta</creatorcontrib><creatorcontrib>Kozioł-Montewka, Maria</creatorcontrib><title>Concurrent peritonsillar abscess and poststreptococcal reactive arthritis complicating acute streptococcal tonsillitis in a young healthy adult: a case report</title><title>BMC infectious diseases</title><addtitle>BMC Infect Dis</addtitle><description>Streptococcus pyogenes is responsible for 5-15% and 20-30% of acute pharyngitis/tonsillitis in adults and children, respectively. It not only causes acute illness but also can give rise to local suppurative complications such as peritonsillar abscess as well as trigger the postinfectious syndromes of glomerulonephritis, acute rheumatic fever and poststreptococcal reactive arthritis. Here, we report a case of a young healthy adult in whom both peritonsillar abscess and poststreptococcal reactive arthritis developed as a complication of acute streptococcal tonsillitis. To the best of our knowledge, such a coincidence of poststreptococcal sequelae has not been reported previously.
A 32-year-old previously healthy woman was diagnosed with acute tonsillitis by her family doctor and treated empirically with amoxicillin/clavulanic acid (875/125 mg) twice daily for 5 days. Four days after completing antibiotic therapy, peritonsillar abscess of left tonsil developed. Needle aspiration followed by incision and drainage were performed by otolaryngologist at the Emergency Department. Next, the patient was discharged home on a 10-day course of cefuroxime and metronidazole. The symptoms of peritonsillar abscess were subsiding during treatment, however on the last day of antibiotic therapy, swelling and pain of the left ankle appeared. Five days later the patient was consulted by rheumatologist. Cultures of throat swabs and abscess aspirate collected 2 weeks before revealed the presence of Streptococcus pyogenes. Antistreptolysin O (ASO) titer was evaluated and proved to be 412 IU/ml (normal 0-200 IU/ml). The level of C-reactive protein was 13,0 mg/L (normal <5,0 mg/L). There was no known cardiac involvement. Poststreptococcal reactive arthritis was diagnosed. Left ankle arthralgia persisted for about 5-6 weeks. Six months after the presentation at the Emergency Department, the patient was well, with ASO titer reaching 262 IU/ml.
Clinicians should be aware that appropriate choice of antibiotic, proper dose as well as duration of therapy of acute GAS pharyngitis/tonsillitis are crucial to prevent poststreptococcal sequelae.</description><subject>Acute Disease</subject><subject>Adult</subject><subject>Arthritis, Infectious</subject><subject>Arthritis, Reactive - diagnosis</subject><subject>Arthritis, Reactive - microbiology</subject><subject>Care and treatment</subject><subject>Case Report</subject><subject>Case studies</subject><subject>Diagnosis</subject><subject>Family medicine</subject><subject>Female</subject><subject>Health aspects</subject><subject>Humans</subject><subject>Infectious arthritis</subject><subject>Patient outcomes</subject><subject>Peritonsillar Abscess - diagnosis</subject><subject>Peritonsillar Abscess - microbiology</subject><subject>Pharyngitis - diagnosis</subject><subject>Pharyngitis - microbiology</subject><subject>Scarlet Fever - complications</subject><subject>Scarlet Fever - diagnosis</subject><subject>Streptococcal Infections - complications</subject><subject>Streptococcus pyogenes - isolation & purification</subject><issn>1471-2334</issn><issn>1471-2334</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNqNkl2L1DAUhoso7of-AG8k4I1edE2atGm9EJbxa2Fhwa_bcJqezEQ6TU3Sxfkz-1vN2HHZwgqSi4ST532TnDdZ9ozRM8bq6nVgRS2bnLIyp7Kmef0gO2ZCsrzgXDy8sz7KTkL4QSmTddE8zo6Ksq7LirLj7GblBj15j0MkI3ob3RBs34Mn0AaNIRAYOjK6EEP0OEanndbQE4-go71GAj5ukswGot127K2GaIc1AT1FJEvNwfsPbAcCZOemhG4Q-rjZEeimPr5JZQ0B0wGj8_FJ9shAH_DpYT7Nvn14_3X1Kb-8-nixOr_M26oqY84qzimXgktWFAI11h10TcENUFGykkEnpDFpNqatWUEpBTSgG9G1VHLD-Gn2dvYdp3aLnU7t8NCr0dst-J1yYNVyZ7AbtXbXSvBCNhVNBu9mg9a6fxgsd1K31JyfSvmpfX6qTjYvD_fw7ueEIaqtTTGkQAZ0U1CskqJqGJVFQl_M6Bp6VHYwLvnqPa7OS8F4Q2W5f9jZPVQaHW6tdgMam-oLwauFIDERf8U1TCGoiy-f_5-9-r5k2cxq70LwaG57w6ja_-Z7u_H8biq3ir_fl_8GsALzww</recordid><startdate>20150207</startdate><enddate>20150207</enddate><creator>Mazur, Elżbieta</creator><creator>Czerwińska, Ewa</creator><creator>Grochowalska, Aneta</creator><creator>Kozioł-Montewka, Maria</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20150207</creationdate><title>Concurrent peritonsillar abscess and poststreptococcal reactive arthritis complicating acute streptococcal tonsillitis in a young healthy adult: a case report</title><author>Mazur, Elżbieta ; Czerwińska, Ewa ; Grochowalska, Aneta ; Kozioł-Montewka, Maria</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b665t-16330374371224ece8dad923fa045151ad47ff51affb812000aefac94db073f13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Acute Disease</topic><topic>Adult</topic><topic>Arthritis, Infectious</topic><topic>Arthritis, Reactive - diagnosis</topic><topic>Arthritis, Reactive - microbiology</topic><topic>Care and treatment</topic><topic>Case Report</topic><topic>Case studies</topic><topic>Diagnosis</topic><topic>Family medicine</topic><topic>Female</topic><topic>Health aspects</topic><topic>Humans</topic><topic>Infectious arthritis</topic><topic>Patient outcomes</topic><topic>Peritonsillar Abscess - diagnosis</topic><topic>Peritonsillar Abscess - microbiology</topic><topic>Pharyngitis - diagnosis</topic><topic>Pharyngitis - microbiology</topic><topic>Scarlet Fever - complications</topic><topic>Scarlet Fever - diagnosis</topic><topic>Streptococcal Infections - complications</topic><topic>Streptococcus pyogenes - isolation & purification</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mazur, Elżbieta</creatorcontrib><creatorcontrib>Czerwińska, Ewa</creatorcontrib><creatorcontrib>Grochowalska, Aneta</creatorcontrib><creatorcontrib>Kozioł-Montewka, Maria</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMC infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mazur, Elżbieta</au><au>Czerwińska, Ewa</au><au>Grochowalska, Aneta</au><au>Kozioł-Montewka, Maria</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Concurrent peritonsillar abscess and poststreptococcal reactive arthritis complicating acute streptococcal tonsillitis in a young healthy adult: a case report</atitle><jtitle>BMC infectious diseases</jtitle><addtitle>BMC Infect Dis</addtitle><date>2015-02-07</date><risdate>2015</risdate><volume>15</volume><issue>1</issue><spage>50</spage><epage>50</epage><pages>50-50</pages><artnum>50</artnum><issn>1471-2334</issn><eissn>1471-2334</eissn><abstract>Streptococcus pyogenes is responsible for 5-15% and 20-30% of acute pharyngitis/tonsillitis in adults and children, respectively. It not only causes acute illness but also can give rise to local suppurative complications such as peritonsillar abscess as well as trigger the postinfectious syndromes of glomerulonephritis, acute rheumatic fever and poststreptococcal reactive arthritis. Here, we report a case of a young healthy adult in whom both peritonsillar abscess and poststreptococcal reactive arthritis developed as a complication of acute streptococcal tonsillitis. To the best of our knowledge, such a coincidence of poststreptococcal sequelae has not been reported previously.
A 32-year-old previously healthy woman was diagnosed with acute tonsillitis by her family doctor and treated empirically with amoxicillin/clavulanic acid (875/125 mg) twice daily for 5 days. Four days after completing antibiotic therapy, peritonsillar abscess of left tonsil developed. Needle aspiration followed by incision and drainage were performed by otolaryngologist at the Emergency Department. Next, the patient was discharged home on a 10-day course of cefuroxime and metronidazole. The symptoms of peritonsillar abscess were subsiding during treatment, however on the last day of antibiotic therapy, swelling and pain of the left ankle appeared. Five days later the patient was consulted by rheumatologist. Cultures of throat swabs and abscess aspirate collected 2 weeks before revealed the presence of Streptococcus pyogenes. Antistreptolysin O (ASO) titer was evaluated and proved to be 412 IU/ml (normal 0-200 IU/ml). The level of C-reactive protein was 13,0 mg/L (normal <5,0 mg/L). There was no known cardiac involvement. Poststreptococcal reactive arthritis was diagnosed. Left ankle arthralgia persisted for about 5-6 weeks. Six months after the presentation at the Emergency Department, the patient was well, with ASO titer reaching 262 IU/ml.
Clinicians should be aware that appropriate choice of antibiotic, proper dose as well as duration of therapy of acute GAS pharyngitis/tonsillitis are crucial to prevent poststreptococcal sequelae.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>25885601</pmid><doi>10.1186/s12879-015-0780-8</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Acute Disease Adult Arthritis, Infectious Arthritis, Reactive - diagnosis Arthritis, Reactive - microbiology Care and treatment Case Report Case studies Diagnosis Family medicine Female Health aspects Humans Infectious arthritis Patient outcomes Peritonsillar Abscess - diagnosis Peritonsillar Abscess - microbiology Pharyngitis - diagnosis Pharyngitis - microbiology Scarlet Fever - complications Scarlet Fever - diagnosis Streptococcal Infections - complications Streptococcus pyogenes - isolation & purification |
title | Concurrent peritonsillar abscess and poststreptococcal reactive arthritis complicating acute streptococcal tonsillitis in a young healthy adult: a case report |
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