Risk Factors for Reduced Salivary Flow Rate in a Japanese Population: The Hisayama Study

The purpose of this study was to determine distinct risk factors causing reduced salivary flow rate in a community-dwelling population using a prospective cohort study design. This was a 5-year follow-up survey of 1,377 community-dwelling Japanese individuals aged ≥40 years. The salivary flow rate w...

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Bibliographic Details
Published in:BioMed research international 2015-01, Vol.2015 (2015), p.1-7
Main Authors: Yamashita, Y., Kiyohara, Yutaka, Akifusa, Sumio, Shimazaki, Yoshihiro, Shibata, Yukie, Takeshita, Toru, Furuta, Michiko, Takeuchi, Kenji, Ninomiya, Toshiharu
Format: Article
Language:English
Subjects:
Adult
Age
Age Factors
Aged
Aging
Asian People
Cohort Studies
Dentistry
Diseases
Female
Health risk assessment
Humans
Japan
Logistic Models
Male
Middle Aged
Population
Prospective Studies
Public health
Risk Factors
Saliva - physiology
Salivary glands
Science
Studies
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Summary:The purpose of this study was to determine distinct risk factors causing reduced salivary flow rate in a community-dwelling population using a prospective cohort study design. This was a 5-year follow-up survey of 1,377 community-dwelling Japanese individuals aged ≥40 years. The salivary flow rate was evaluated at baseline and follow-up by collecting stimulated saliva. Data on demographic characteristics, use of medication, and general and oral health status were obtained at baseline. The relationship between reduced salivary flow rate during the follow-up period and its predictors was evaluated after adjustment for confounding factors. In a multivariate logistic regression model, higher age and plaque score and lower serum albumin levels were significantly associated with greater odds of an obvious reduction in salivary flow rate (age per decade, odds ratio [OR] = 1.25, 95% confidence interval [CI] = 1.03–1.51; serum albumin levels
ISSN:2314-6133
2314-6141
DOI:10.1155/2015/381821