Loading…
Genotypic characterization of amoeba isolated from Acanthamoeba keratitis in Poland
Free-living amoebae belonging to the genus Acanthamoeba are the causative factor of many diseases. Among others, they cause Acanthamoeba keratitis (AK), a condition that usually occurs in contact lens wearers, though it is also observed in non-wearers. The number of diagnosed cases of AK increased m...
Saved in:
| Published in: | Parasitology research (1987) 2015-03, Vol.114 (3), p.1233-1237 |
|---|---|
| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c603t-391584d137f4445bf5df238c3a8c35b38a4b8fb1b1bcab747d2659fb7eca3d0b3 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c603t-391584d137f4445bf5df238c3a8c35b38a4b8fb1b1bcab747d2659fb7eca3d0b3 |
| container_end_page | 1237 |
| container_issue | 3 |
| container_start_page | 1233 |
| container_title | Parasitology research (1987) |
| container_volume | 114 |
| creator | Derda, Monika Solarczyk, Piotr Cholewiński, Marcin Hadaś, Edward |
| description | Free-living amoebae belonging to the genus Acanthamoeba are the causative factor of many diseases. Among others, they cause Acanthamoeba keratitis (AK), a condition that usually occurs in contact lens wearers, though it is also observed in non-wearers. The number of diagnosed cases of AK increased more than eightfold during 8 years in the USA, and a proportional increase in frequency also occurred in Poland and Europe. Cases of AK are usually diagnosed late, and their therapy is difficult and rarely successful. AK is an uncommon diagnosis in Poland. The increased number of positive cases observed in our laboratory may reflect the growing at-risk population of contact lens wearers. Acanthamoeba as a genus of facultative human parasites is currently classified into 17 genotypes. Isolates belonging to seven genotypes were found to be associated with AK. One genotype in particular, T4, was found to be overrepresented in human disease. The main finding of our study is that in Poland, AK is almost always associated with the T4 genotype. |
| doi_str_mv | 10.1007/s00436-015-4319-0 |
| format | article |
| fullrecord | <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4336404</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A424632754</galeid><sourcerecordid>A424632754</sourcerecordid><originalsourceid>FETCH-LOGICAL-c603t-391584d137f4445bf5df238c3a8c35b38a4b8fb1b1bcab747d2659fb7eca3d0b3</originalsourceid><addsrcrecordid>eNp9kl9rFDEUxYNY7Lr6AXzRAV98mZpM_u28CEupVSgo1D6HJJPsps4ka5IV2k_vXWYtFoqEkJD7O4fcnCD0huAzgrH8WDBmVLSY8JZR0rf4GVoQRruW9Jw_Rwvcwx4TQk_Ry1JuMSZSMPYCnXZcYCYkXaDrSxdTvdsF29itztpWl8O9riHFJvlGT8kZ3YSSRl3d0PicpmZtdazbY-mny0DXUJoQm--AxeEVOvF6LO71cV2im88XP86_tFffLr-er69aKzCtLe0JX7GBUOkZY9x4PviOrizVMLmhK83MyhsCw2ojmRw6wXtvpLOaDtjQJfo0--72ZnKDdbFmPapdDpPOdyrpoB5XYtiqTfqtGKWCwdMt0YejQU6_9q5UNYVi3QhNuLQvigguaScxvNQSvZ_RjR6dCtEncLQHXK1ZxwRg_GB49gQFY3BTsCk6H-D8kYDMAptTKdn5h9sTrA4ZqzljBRmrQ8YKg-btv20_KP6GCkA3AwVKceOyuk37HCGK_7q-m0VeJ6U3ORR1c90BAL-G9kII-gd1mLtU</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1657327067</pqid></control><display><type>article</type><title>Genotypic characterization of amoeba isolated from Acanthamoeba keratitis in Poland</title><source>Springer Link</source><creator>Derda, Monika ; Solarczyk, Piotr ; Cholewiński, Marcin ; Hadaś, Edward</creator><creatorcontrib>Derda, Monika ; Solarczyk, Piotr ; Cholewiński, Marcin ; Hadaś, Edward</creatorcontrib><description>Free-living amoebae belonging to the genus Acanthamoeba are the causative factor of many diseases. Among others, they cause Acanthamoeba keratitis (AK), a condition that usually occurs in contact lens wearers, though it is also observed in non-wearers. The number of diagnosed cases of AK increased more than eightfold during 8 years in the USA, and a proportional increase in frequency also occurred in Poland and Europe. Cases of AK are usually diagnosed late, and their therapy is difficult and rarely successful. AK is an uncommon diagnosis in Poland. The increased number of positive cases observed in our laboratory may reflect the growing at-risk population of contact lens wearers. Acanthamoeba as a genus of facultative human parasites is currently classified into 17 genotypes. Isolates belonging to seven genotypes were found to be associated with AK. One genotype in particular, T4, was found to be overrepresented in human disease. The main finding of our study is that in Poland, AK is almost always associated with the T4 genotype.</description><identifier>ISSN: 0932-0113</identifier><identifier>EISSN: 1432-1955</identifier><identifier>DOI: 10.1007/s00436-015-4319-0</identifier><identifier>PMID: 25604673</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Acanthamoeba ; Acanthamoeba - genetics ; Acanthamoeba Keratitis - epidemiology ; Acanthamoeba Keratitis - parasitology ; Amoeba ; Amoebas ; at-risk population ; Biomedical and Life Sciences ; Biomedicine ; Europe ; Female ; Genetic aspects ; Genotype ; Genotypes ; Health aspects ; Host-parasite relationships ; human diseases ; Humans ; Identification and classification ; Immunology ; Keratitis ; Male ; Medical Microbiology ; Microbiology ; parasites ; parasitology ; Poland - epidemiology ; Short Communication ; therapeutics</subject><ispartof>Parasitology research (1987), 2015-03, Vol.114 (3), p.1233-1237</ispartof><rights>The Author(s) 2015</rights><rights>COPYRIGHT 2015 Springer</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c603t-391584d137f4445bf5df238c3a8c35b38a4b8fb1b1bcab747d2659fb7eca3d0b3</citedby><cites>FETCH-LOGICAL-c603t-391584d137f4445bf5df238c3a8c35b38a4b8fb1b1bcab747d2659fb7eca3d0b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25604673$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Derda, Monika</creatorcontrib><creatorcontrib>Solarczyk, Piotr</creatorcontrib><creatorcontrib>Cholewiński, Marcin</creatorcontrib><creatorcontrib>Hadaś, Edward</creatorcontrib><title>Genotypic characterization of amoeba isolated from Acanthamoeba keratitis in Poland</title><title>Parasitology research (1987)</title><addtitle>Parasitol Res</addtitle><addtitle>Parasitol Res</addtitle><description>Free-living amoebae belonging to the genus Acanthamoeba are the causative factor of many diseases. Among others, they cause Acanthamoeba keratitis (AK), a condition that usually occurs in contact lens wearers, though it is also observed in non-wearers. The number of diagnosed cases of AK increased more than eightfold during 8 years in the USA, and a proportional increase in frequency also occurred in Poland and Europe. Cases of AK are usually diagnosed late, and their therapy is difficult and rarely successful. AK is an uncommon diagnosis in Poland. The increased number of positive cases observed in our laboratory may reflect the growing at-risk population of contact lens wearers. Acanthamoeba as a genus of facultative human parasites is currently classified into 17 genotypes. Isolates belonging to seven genotypes were found to be associated with AK. One genotype in particular, T4, was found to be overrepresented in human disease. The main finding of our study is that in Poland, AK is almost always associated with the T4 genotype.</description><subject>Acanthamoeba</subject><subject>Acanthamoeba - genetics</subject><subject>Acanthamoeba Keratitis - epidemiology</subject><subject>Acanthamoeba Keratitis - parasitology</subject><subject>Amoeba</subject><subject>Amoebas</subject><subject>at-risk population</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Europe</subject><subject>Female</subject><subject>Genetic aspects</subject><subject>Genotype</subject><subject>Genotypes</subject><subject>Health aspects</subject><subject>Host-parasite relationships</subject><subject>human diseases</subject><subject>Humans</subject><subject>Identification and classification</subject><subject>Immunology</subject><subject>Keratitis</subject><subject>Male</subject><subject>Medical Microbiology</subject><subject>Microbiology</subject><subject>parasites</subject><subject>parasitology</subject><subject>Poland - epidemiology</subject><subject>Short Communication</subject><subject>therapeutics</subject><issn>0932-0113</issn><issn>1432-1955</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNp9kl9rFDEUxYNY7Lr6AXzRAV98mZpM_u28CEupVSgo1D6HJJPsps4ka5IV2k_vXWYtFoqEkJD7O4fcnCD0huAzgrH8WDBmVLSY8JZR0rf4GVoQRruW9Jw_Rwvcwx4TQk_Ry1JuMSZSMPYCnXZcYCYkXaDrSxdTvdsF29itztpWl8O9riHFJvlGT8kZ3YSSRl3d0PicpmZtdazbY-mny0DXUJoQm--AxeEVOvF6LO71cV2im88XP86_tFffLr-er69aKzCtLe0JX7GBUOkZY9x4PviOrizVMLmhK83MyhsCw2ojmRw6wXtvpLOaDtjQJfo0--72ZnKDdbFmPapdDpPOdyrpoB5XYtiqTfqtGKWCwdMt0YejQU6_9q5UNYVi3QhNuLQvigguaScxvNQSvZ_RjR6dCtEncLQHXK1ZxwRg_GB49gQFY3BTsCk6H-D8kYDMAptTKdn5h9sTrA4ZqzljBRmrQ8YKg-btv20_KP6GCkA3AwVKceOyuk37HCGK_7q-m0VeJ6U3ORR1c90BAL-G9kII-gd1mLtU</recordid><startdate>20150301</startdate><enddate>20150301</enddate><creator>Derda, Monika</creator><creator>Solarczyk, Piotr</creator><creator>Cholewiński, Marcin</creator><creator>Hadaś, Edward</creator><general>Springer-Verlag</general><general>Springer Berlin Heidelberg</general><general>Springer</general><scope>FBQ</scope><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20150301</creationdate><title>Genotypic characterization of amoeba isolated from Acanthamoeba keratitis in Poland</title><author>Derda, Monika ; Solarczyk, Piotr ; Cholewiński, Marcin ; Hadaś, Edward</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c603t-391584d137f4445bf5df238c3a8c35b38a4b8fb1b1bcab747d2659fb7eca3d0b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Acanthamoeba</topic><topic>Acanthamoeba - genetics</topic><topic>Acanthamoeba Keratitis - epidemiology</topic><topic>Acanthamoeba Keratitis - parasitology</topic><topic>Amoeba</topic><topic>Amoebas</topic><topic>at-risk population</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Europe</topic><topic>Female</topic><topic>Genetic aspects</topic><topic>Genotype</topic><topic>Genotypes</topic><topic>Health aspects</topic><topic>Host-parasite relationships</topic><topic>human diseases</topic><topic>Humans</topic><topic>Identification and classification</topic><topic>Immunology</topic><topic>Keratitis</topic><topic>Male</topic><topic>Medical Microbiology</topic><topic>Microbiology</topic><topic>parasites</topic><topic>parasitology</topic><topic>Poland - epidemiology</topic><topic>Short Communication</topic><topic>therapeutics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Derda, Monika</creatorcontrib><creatorcontrib>Solarczyk, Piotr</creatorcontrib><creatorcontrib>Cholewiński, Marcin</creatorcontrib><creatorcontrib>Hadaś, Edward</creatorcontrib><collection>AGRIS</collection><collection>SpringerOpen (Open Access)</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Parasitology research (1987)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Derda, Monika</au><au>Solarczyk, Piotr</au><au>Cholewiński, Marcin</au><au>Hadaś, Edward</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Genotypic characterization of amoeba isolated from Acanthamoeba keratitis in Poland</atitle><jtitle>Parasitology research (1987)</jtitle><stitle>Parasitol Res</stitle><addtitle>Parasitol Res</addtitle><date>2015-03-01</date><risdate>2015</risdate><volume>114</volume><issue>3</issue><spage>1233</spage><epage>1237</epage><pages>1233-1237</pages><issn>0932-0113</issn><eissn>1432-1955</eissn><abstract>Free-living amoebae belonging to the genus Acanthamoeba are the causative factor of many diseases. Among others, they cause Acanthamoeba keratitis (AK), a condition that usually occurs in contact lens wearers, though it is also observed in non-wearers. The number of diagnosed cases of AK increased more than eightfold during 8 years in the USA, and a proportional increase in frequency also occurred in Poland and Europe. Cases of AK are usually diagnosed late, and their therapy is difficult and rarely successful. AK is an uncommon diagnosis in Poland. The increased number of positive cases observed in our laboratory may reflect the growing at-risk population of contact lens wearers. Acanthamoeba as a genus of facultative human parasites is currently classified into 17 genotypes. Isolates belonging to seven genotypes were found to be associated with AK. One genotype in particular, T4, was found to be overrepresented in human disease. The main finding of our study is that in Poland, AK is almost always associated with the T4 genotype.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>25604673</pmid><doi>10.1007/s00436-015-4319-0</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0932-0113 |
| ispartof | Parasitology research (1987), 2015-03, Vol.114 (3), p.1233-1237 |
| issn | 0932-0113 1432-1955 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4336404 |
| source | Springer Link |
| subjects | Acanthamoeba Acanthamoeba - genetics Acanthamoeba Keratitis - epidemiology Acanthamoeba Keratitis - parasitology Amoeba Amoebas at-risk population Biomedical and Life Sciences Biomedicine Europe Female Genetic aspects Genotype Genotypes Health aspects Host-parasite relationships human diseases Humans Identification and classification Immunology Keratitis Male Medical Microbiology Microbiology parasites parasitology Poland - epidemiology Short Communication therapeutics |
| title | Genotypic characterization of amoeba isolated from Acanthamoeba keratitis in Poland |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-11T10%3A07%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Genotypic%20characterization%20of%20amoeba%20isolated%20from%20Acanthamoeba%20keratitis%20in%20Poland&rft.jtitle=Parasitology%20research%20(1987)&rft.au=Derda,%20Monika&rft.date=2015-03-01&rft.volume=114&rft.issue=3&rft.spage=1233&rft.epage=1237&rft.pages=1233-1237&rft.issn=0932-0113&rft.eissn=1432-1955&rft_id=info:doi/10.1007/s00436-015-4319-0&rft_dat=%3Cgale_pubme%3EA424632754%3C/gale_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c603t-391584d137f4445bf5df238c3a8c35b38a4b8fb1b1bcab747d2659fb7eca3d0b3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1657327067&rft_id=info:pmid/25604673&rft_galeid=A424632754&rfr_iscdi=true |