Myocardial function in aortic stenosis--insights from radial multilayer Doppler strain

Left ventricular (LV) radial tissue Doppler imaging (TDI) strain increases gradually from the subepicardial to the subendocardial layer in healthy individuals. A speckle tracking echocardiography study suggested this gradient to be reduced in parallel with increasing aortic stenosis (AS) severity. W...

Full description

Saved in:
Bibliographic Details
Published in:Cardiovascular ultrasound 2015-02, Vol.13 (1), p.8-8, Article 8
Main Authors: Cramariuc, Dana, Gerdts, Eva, Hjertaas, Johannes Just, Cramariuc, Alexandru, Davidsen, Einar Skulstad, Matre, Knut
Format: Article
Language:English
Subjects:
Aged
Anisotropy
Aortic Valve Stenosis - complications
Aortic Valve Stenosis - diagnostic imaging
Aortic Valve Stenosis - physiopathology
Compressive Strength
Echocardiography, Doppler - methods
Elastic Modulus
Female
Humans
Male
Reproducibility of Results
Sensitivity and Specificity
Shear Strength
Stress, Mechanical
Tensile Strength
Ventricular Dysfunction, Left - diagnostic imaging
Ventricular Dysfunction, Left - etiology
Ventricular Dysfunction, Left - physiopathology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-b527t-1b6df448189213812972c355c3d49ad0f74c885a172ddc9c3183b574eab6fd13
cites cdi_FETCH-LOGICAL-b527t-1b6df448189213812972c355c3d49ad0f74c885a172ddc9c3183b574eab6fd13
container_end_page 8
container_issue 1
container_start_page 8
container_title Cardiovascular ultrasound
container_volume 13
creator Cramariuc, Dana
Gerdts, Eva
Hjertaas, Johannes Just
Cramariuc, Alexandru
Davidsen, Einar Skulstad
Matre, Knut
description Left ventricular (LV) radial tissue Doppler imaging (TDI) strain increases gradually from the subepicardial to the subendocardial layer in healthy individuals. A speckle tracking echocardiography study suggested this gradient to be reduced in parallel with increasing aortic stenosis (AS) severity. We used TDI strain in 84 patients with AS (mean age 73 ± 10 years, 56% hypertensive) for superior assessment of layer strain. 38 patients had non-severe and 46 severe AS by aortic valve area corrected for pressure recovery. Peak systolic radial TDI strain was measured in the subendocardial, mid-myocardial and subepicardial layers of the basal inferior LV wall, each within a region of interest of 2 × 6 mm (strain length 2 mm). Radial strain was lower in the subepicardial layer (33.4 ± 38.6%) compared to the mid-myocardial and subendocardial layers (50.3 ± 37.3% and 53.0 ± 40.0%, respectively, both p 
doi_str_mv 10.1186/s12947-015-0001-z
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4340885</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1674685664</sourcerecordid><originalsourceid>FETCH-LOGICAL-b527t-1b6df448189213812972c355c3d49ad0f74c885a172ddc9c3183b574eab6fd13</originalsourceid><addsrcrecordid>eNp1kU1LxDAQhoMoun78AC_So5dopkmT9CLI-gmKF_Ea0jTdjbTJmrTC-uvtuioKepqBmXnmnXcQOgRyAiD5aYK8ZAITKDAhBPDbBpoAExwLyMnmj3wH7ab0TEieA5XbaCcvZEko4RP0dL8MRsfa6TZrBm96F3zmfKZD7J3JUm99SC5h7Hxys3mfsiaGLov6Y6Ib2t61emljdhEWi3aMqY_a-X201eg22YPPuIcery4fpzf47uH6dnp-h6siFz2GitcNYxJkuVI2niNyQ4vC0JqVuiaNYEbKQoPI69qUhoKkVSGY1RVvaqB76GyNXQxVZ2tj_bi9VYvoOh2XKminfle8m6tZeFWMMjKCR8DFGlC58A_gd8WETq1tV6PtamW7ehsxx586YngZbOpV55Kxbau9DUNSwAXjsuCcja2wbjUxpBRt870MiFp99U_80c8zvye-3kjfAc2MoNM</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1674685664</pqid></control><display><type>article</type><title>Myocardial function in aortic stenosis--insights from radial multilayer Doppler strain</title><source>Publicly Available Content Database (Proquest) (PQ_SDU_P3)</source><source>PubMed Central(OpenAccess)</source><creator>Cramariuc, Dana ; Gerdts, Eva ; Hjertaas, Johannes Just ; Cramariuc, Alexandru ; Davidsen, Einar Skulstad ; Matre, Knut</creator><creatorcontrib>Cramariuc, Dana ; Gerdts, Eva ; Hjertaas, Johannes Just ; Cramariuc, Alexandru ; Davidsen, Einar Skulstad ; Matre, Knut</creatorcontrib><description>Left ventricular (LV) radial tissue Doppler imaging (TDI) strain increases gradually from the subepicardial to the subendocardial layer in healthy individuals. A speckle tracking echocardiography study suggested this gradient to be reduced in parallel with increasing aortic stenosis (AS) severity. We used TDI strain in 84 patients with AS (mean age 73 ± 10 years, 56% hypertensive) for superior assessment of layer strain. 38 patients had non-severe and 46 severe AS by aortic valve area corrected for pressure recovery. Peak systolic radial TDI strain was measured in the subendocardial, mid-myocardial and subepicardial layers of the basal inferior LV wall, each within a region of interest of 2 × 6 mm (strain length 2 mm). Radial strain was lower in the subepicardial layer (33.4 ± 38.6%) compared to the mid-myocardial and subendocardial layers (50.3 ± 37.3% and 53.0 ± 40.0%, respectively, both p &lt; 0.001 vs. subepicardial). In the subendo- and midmyocardium, radial strain was lower in patients with severe AS compared to those with non-severe AS (p &lt; 0.05). In multivariate regression analyses including age, heart rate, inferior wall thickness, hypertension, and AS severity, radial strain in the mid-myocardium was primarily attenuated by presence of hypertension (β = -0.23) and AS severity (β = -0.26, both p &lt; 0.05), while radial strain in the subendocardium was significantly influenced by AS severity only (β = -0.35, p &lt; 0.01). In AS, both the AS severity and concomitant hypertension attenuate radial TDI strain in the inferior LV wall. The subendocardial radial strain is mainly influenced by AS severity, while midmyocardial radial strain is attenuated by both hypertension and AS severity.</description><identifier>ISSN: 1476-7120</identifier><identifier>EISSN: 1476-7120</identifier><identifier>DOI: 10.1186/s12947-015-0001-z</identifier><identifier>PMID: 25890306</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Aged ; Anisotropy ; Aortic Valve Stenosis - complications ; Aortic Valve Stenosis - diagnostic imaging ; Aortic Valve Stenosis - physiopathology ; Compressive Strength ; Echocardiography, Doppler - methods ; Elastic Modulus ; Female ; Humans ; Male ; Reproducibility of Results ; Sensitivity and Specificity ; Shear Strength ; Stress, Mechanical ; Tensile Strength ; Ventricular Dysfunction, Left - diagnostic imaging ; Ventricular Dysfunction, Left - etiology ; Ventricular Dysfunction, Left - physiopathology</subject><ispartof>Cardiovascular ultrasound, 2015-02, Vol.13 (1), p.8-8, Article 8</ispartof><rights>Cramariuc et al.; licensee BioMed Central. 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b527t-1b6df448189213812972c355c3d49ad0f74c885a172ddc9c3183b574eab6fd13</citedby><cites>FETCH-LOGICAL-b527t-1b6df448189213812972c355c3d49ad0f74c885a172ddc9c3183b574eab6fd13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340885/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340885/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,37013,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25890306$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cramariuc, Dana</creatorcontrib><creatorcontrib>Gerdts, Eva</creatorcontrib><creatorcontrib>Hjertaas, Johannes Just</creatorcontrib><creatorcontrib>Cramariuc, Alexandru</creatorcontrib><creatorcontrib>Davidsen, Einar Skulstad</creatorcontrib><creatorcontrib>Matre, Knut</creatorcontrib><title>Myocardial function in aortic stenosis--insights from radial multilayer Doppler strain</title><title>Cardiovascular ultrasound</title><addtitle>Cardiovasc Ultrasound</addtitle><description>Left ventricular (LV) radial tissue Doppler imaging (TDI) strain increases gradually from the subepicardial to the subendocardial layer in healthy individuals. A speckle tracking echocardiography study suggested this gradient to be reduced in parallel with increasing aortic stenosis (AS) severity. We used TDI strain in 84 patients with AS (mean age 73 ± 10 years, 56% hypertensive) for superior assessment of layer strain. 38 patients had non-severe and 46 severe AS by aortic valve area corrected for pressure recovery. Peak systolic radial TDI strain was measured in the subendocardial, mid-myocardial and subepicardial layers of the basal inferior LV wall, each within a region of interest of 2 × 6 mm (strain length 2 mm). Radial strain was lower in the subepicardial layer (33.4 ± 38.6%) compared to the mid-myocardial and subendocardial layers (50.3 ± 37.3% and 53.0 ± 40.0%, respectively, both p &lt; 0.001 vs. subepicardial). In the subendo- and midmyocardium, radial strain was lower in patients with severe AS compared to those with non-severe AS (p &lt; 0.05). In multivariate regression analyses including age, heart rate, inferior wall thickness, hypertension, and AS severity, radial strain in the mid-myocardium was primarily attenuated by presence of hypertension (β = -0.23) and AS severity (β = -0.26, both p &lt; 0.05), while radial strain in the subendocardium was significantly influenced by AS severity only (β = -0.35, p &lt; 0.01). In AS, both the AS severity and concomitant hypertension attenuate radial TDI strain in the inferior LV wall. The subendocardial radial strain is mainly influenced by AS severity, while midmyocardial radial strain is attenuated by both hypertension and AS severity.</description><subject>Aged</subject><subject>Anisotropy</subject><subject>Aortic Valve Stenosis - complications</subject><subject>Aortic Valve Stenosis - diagnostic imaging</subject><subject>Aortic Valve Stenosis - physiopathology</subject><subject>Compressive Strength</subject><subject>Echocardiography, Doppler - methods</subject><subject>Elastic Modulus</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Reproducibility of Results</subject><subject>Sensitivity and Specificity</subject><subject>Shear Strength</subject><subject>Stress, Mechanical</subject><subject>Tensile Strength</subject><subject>Ventricular Dysfunction, Left - diagnostic imaging</subject><subject>Ventricular Dysfunction, Left - etiology</subject><subject>Ventricular Dysfunction, Left - physiopathology</subject><issn>1476-7120</issn><issn>1476-7120</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNp1kU1LxDAQhoMoun78AC_So5dopkmT9CLI-gmKF_Ea0jTdjbTJmrTC-uvtuioKepqBmXnmnXcQOgRyAiD5aYK8ZAITKDAhBPDbBpoAExwLyMnmj3wH7ab0TEieA5XbaCcvZEko4RP0dL8MRsfa6TZrBm96F3zmfKZD7J3JUm99SC5h7Hxys3mfsiaGLov6Y6Ib2t61emljdhEWi3aMqY_a-X201eg22YPPuIcery4fpzf47uH6dnp-h6siFz2GitcNYxJkuVI2niNyQ4vC0JqVuiaNYEbKQoPI69qUhoKkVSGY1RVvaqB76GyNXQxVZ2tj_bi9VYvoOh2XKminfle8m6tZeFWMMjKCR8DFGlC58A_gd8WETq1tV6PtamW7ehsxx586YngZbOpV55Kxbau9DUNSwAXjsuCcja2wbjUxpBRt870MiFp99U_80c8zvye-3kjfAc2MoNM</recordid><startdate>20150219</startdate><enddate>20150219</enddate><creator>Cramariuc, Dana</creator><creator>Gerdts, Eva</creator><creator>Hjertaas, Johannes Just</creator><creator>Cramariuc, Alexandru</creator><creator>Davidsen, Einar Skulstad</creator><creator>Matre, Knut</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20150219</creationdate><title>Myocardial function in aortic stenosis--insights from radial multilayer Doppler strain</title><author>Cramariuc, Dana ; Gerdts, Eva ; Hjertaas, Johannes Just ; Cramariuc, Alexandru ; Davidsen, Einar Skulstad ; Matre, Knut</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b527t-1b6df448189213812972c355c3d49ad0f74c885a172ddc9c3183b574eab6fd13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Aged</topic><topic>Anisotropy</topic><topic>Aortic Valve Stenosis - complications</topic><topic>Aortic Valve Stenosis - diagnostic imaging</topic><topic>Aortic Valve Stenosis - physiopathology</topic><topic>Compressive Strength</topic><topic>Echocardiography, Doppler - methods</topic><topic>Elastic Modulus</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Reproducibility of Results</topic><topic>Sensitivity and Specificity</topic><topic>Shear Strength</topic><topic>Stress, Mechanical</topic><topic>Tensile Strength</topic><topic>Ventricular Dysfunction, Left - diagnostic imaging</topic><topic>Ventricular Dysfunction, Left - etiology</topic><topic>Ventricular Dysfunction, Left - physiopathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cramariuc, Dana</creatorcontrib><creatorcontrib>Gerdts, Eva</creatorcontrib><creatorcontrib>Hjertaas, Johannes Just</creatorcontrib><creatorcontrib>Cramariuc, Alexandru</creatorcontrib><creatorcontrib>Davidsen, Einar Skulstad</creatorcontrib><creatorcontrib>Matre, Knut</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Cardiovascular ultrasound</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cramariuc, Dana</au><au>Gerdts, Eva</au><au>Hjertaas, Johannes Just</au><au>Cramariuc, Alexandru</au><au>Davidsen, Einar Skulstad</au><au>Matre, Knut</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Myocardial function in aortic stenosis--insights from radial multilayer Doppler strain</atitle><jtitle>Cardiovascular ultrasound</jtitle><addtitle>Cardiovasc Ultrasound</addtitle><date>2015-02-19</date><risdate>2015</risdate><volume>13</volume><issue>1</issue><spage>8</spage><epage>8</epage><pages>8-8</pages><artnum>8</artnum><issn>1476-7120</issn><eissn>1476-7120</eissn><abstract>Left ventricular (LV) radial tissue Doppler imaging (TDI) strain increases gradually from the subepicardial to the subendocardial layer in healthy individuals. A speckle tracking echocardiography study suggested this gradient to be reduced in parallel with increasing aortic stenosis (AS) severity. We used TDI strain in 84 patients with AS (mean age 73 ± 10 years, 56% hypertensive) for superior assessment of layer strain. 38 patients had non-severe and 46 severe AS by aortic valve area corrected for pressure recovery. Peak systolic radial TDI strain was measured in the subendocardial, mid-myocardial and subepicardial layers of the basal inferior LV wall, each within a region of interest of 2 × 6 mm (strain length 2 mm). Radial strain was lower in the subepicardial layer (33.4 ± 38.6%) compared to the mid-myocardial and subendocardial layers (50.3 ± 37.3% and 53.0 ± 40.0%, respectively, both p &lt; 0.001 vs. subepicardial). In the subendo- and midmyocardium, radial strain was lower in patients with severe AS compared to those with non-severe AS (p &lt; 0.05). In multivariate regression analyses including age, heart rate, inferior wall thickness, hypertension, and AS severity, radial strain in the mid-myocardium was primarily attenuated by presence of hypertension (β = -0.23) and AS severity (β = -0.26, both p &lt; 0.05), while radial strain in the subendocardium was significantly influenced by AS severity only (β = -0.35, p &lt; 0.01). In AS, both the AS severity and concomitant hypertension attenuate radial TDI strain in the inferior LV wall. The subendocardial radial strain is mainly influenced by AS severity, while midmyocardial radial strain is attenuated by both hypertension and AS severity.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>25890306</pmid><doi>10.1186/s12947-015-0001-z</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1476-7120
ispartof Cardiovascular ultrasound, 2015-02, Vol.13 (1), p.8-8, Article 8
issn 1476-7120
1476-7120
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4340885
source Publicly Available Content Database (Proquest) (PQ_SDU_P3); PubMed Central(OpenAccess)
subjects Aged
Anisotropy
Aortic Valve Stenosis - complications
Aortic Valve Stenosis - diagnostic imaging
Aortic Valve Stenosis - physiopathology
Compressive Strength
Echocardiography, Doppler - methods
Elastic Modulus
Female
Humans
Male
Reproducibility of Results
Sensitivity and Specificity
Shear Strength
Stress, Mechanical
Tensile Strength
Ventricular Dysfunction, Left - diagnostic imaging
Ventricular Dysfunction, Left - etiology
Ventricular Dysfunction, Left - physiopathology
title Myocardial function in aortic stenosis--insights from radial multilayer Doppler strain
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T11%3A34%3A07IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Myocardial%20function%20in%20aortic%20stenosis--insights%20from%20radial%20multilayer%20Doppler%20strain&rft.jtitle=Cardiovascular%20ultrasound&rft.au=Cramariuc,%20Dana&rft.date=2015-02-19&rft.volume=13&rft.issue=1&rft.spage=8&rft.epage=8&rft.pages=8-8&rft.artnum=8&rft.issn=1476-7120&rft.eissn=1476-7120&rft_id=info:doi/10.1186/s12947-015-0001-z&rft_dat=%3Cproquest_pubme%3E1674685664%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-b527t-1b6df448189213812972c355c3d49ad0f74c885a172ddc9c3183b574eab6fd13%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1674685664&rft_id=info:pmid/25890306&rfr_iscdi=true