The Use of Octreotide to Manage Symptoms of Bronchorrhea: A Case Report

Abstract Octreotide, a synthetic analogue of the hormone somatostatin, is primarily used in palliative medicine because of its antisecretory effect and has been shown to be effective in the management of bowel obstruction, nausea, and diarrhea. Octreotide also has been successfully used for the mana...

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Bibliographic Details
Published in:Journal of pain and symptom management 2014-04, Vol.47 (4), p.814-818
Main Authors: Pahuja, Meera, MD, MSc, Shepherd, Ray W., MD, Lyckholm, Laurel J., MD
Format: Article
Language:English
Subjects:
Adenocarcinoma, Bronchiolo-Alveolar - complications
Adenocarcinoma, Bronchiolo-Alveolar - physiopathology
Adenocarcinoma, Bronchiolo-Alveolar - therapy
Anesthesia & Perioperative Care
Antineoplastic Agents, Hormonal - therapeutic use
Biological and medical sciences
Bronchi - drug effects
Bronchi - secretion
Bronchial Diseases - drug therapy
Bronchial Diseases - etiology
Bronchial Diseases - physiopathology
bronchioloalveolar carcinoma
Bronchorrhea
Cancer
Female
Hormones
Humans
Lung Neoplasms - complications
Lung Neoplasms - physiopathology
Lung Neoplasms - therapy
Medical sciences
Middle Aged
Multiple tumors. Solid tumors. Tumors in childhood (general aspects)
Nausea
Obstruction
octreotide
Octreotide - therapeutic use
Pain Medicine
Palliative Care
Palliative medicine
Pharmacology. Drug treatments
Pneumology
Symptoms
Tumors
Tumors of the respiratory system and mediastinum
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Summary:Abstract Octreotide, a synthetic analogue of the hormone somatostatin, is primarily used in palliative medicine because of its antisecretory effect and has been shown to be effective in the management of bowel obstruction, nausea, and diarrhea. Octreotide also has been successfully used for the management of bronchorrhea in both inpatient and outpatient settings. We report the case of a 47-year-old female with a history of bronchioloalveolar cell carcinoma whose copious bronchial secretions were controlled with octreotide. Octreotide should be further evaluated as a first-line treatment for bronchorrhea.
ISSN:0885-3924
1873-6513
DOI:10.1016/j.jpainsymman.2013.06.008