The effects of sarcolipin over-expression in mouse skeletal muscle on metabolic activity

•Sarcolipin is insufficient to affect thermogenic activity of SERCA in mouse muscle.•The ratio of SLN to SERCA in total limb skeletal muscle is

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Bibliographic Details
Published in:Archives of biochemistry and biophysics 2015-03, Vol.569, p.26-31
Main Authors: Butler, John, Smyth, Neil, Broadbridge, Robert, Council, Claire E., Lee, Anthony G., Stocker, Claire J., Hislop, David C., Arch, Jonathan R.S., Cawthorne, Michael A., Malcolm East, J.
Format: Article
Language:English
Subjects:
Animals
Body Weight - genetics
Body Weight - physiology
Diet, High-Fat
Energy expenditure
Energy Metabolism - genetics
Energy Metabolism - physiology
High fat diet
Male
Mice
Mice, Transgenic
Muscle Proteins - genetics
Muscle Proteins - metabolism
Muscle, Skeletal - metabolism
Obesity
Oligopeptides - genetics
Oligopeptides - metabolism
Proteolipids - genetics
Proteolipids - metabolism
Recombinant Fusion Proteins - genetics
Recombinant Fusion Proteins - metabolism
Sarcolipin
Sarcoplasmic Reticulum Calcium-Transporting ATPases - metabolism
SERCA
Thermogenesis
Thermogenesis - genetics
Thermogenesis - physiology
Up-Regulation
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Description
Summary:•Sarcolipin is insufficient to affect thermogenic activity of SERCA in mouse muscle.•The ratio of SLN to SERCA in total limb skeletal muscle is
ISSN:0003-9861
1096-0384
DOI:10.1016/j.abb.2015.01.027